Craniofacial Oral-biology Student Training in Academic Research (COSTAR)

说明（由申请人提供）：本申请为T32综合机构研究训练补助金COSTAR（颅面口腔生物学学生学术研究训练）的续期申请。自2002年首次资助以来，COSTAR已培养了14名DDS/博士研究生，24名博士研究生，17名博士后，4名教师，93名暑期牙科学生研究人员。自2002年以来，我们的结果测量表明了一个出色的培训环境，如学员发表的270篇同行评议论文所记录的，包括Nature和PNAS， 19名学员（35%）获得并转移到NIH的个人奖励（F30, F31, F32, K08， K23或R21）或同等奖学金。我们对前高级学位COSTAR受训者、毕业生和研究员的跟踪显示，他们在研究领域的保留率（82%）堪称典范，包括学术或科学家职位或继续博士后研究培训。COSTAR项目在促进多样性方面取得了巨大进展，招募了44%的未被充分代表的少数民族和73%的女性学员。根据这些衡量成功的客观标准和我们不断进行的自我评估进程，我们建议将支助期限再延长5年。我们的重点目标仍然是致力于培养一批高技能，互动的科学家，他们能够成功地应对牙科，口腔和颅面研究的新机遇，并成为美国牙科学校未来学术教师的一部分。COSTAR计划将提供三个综合培训轨道：1)DDS/PhD计划，2)PhD计划，以及3)基础或临床转化博士后研究奖学金。这三个培训课程由三个综合的主题领域提供，由一个经过精心挑选的，研究密集的，合作的项目教师代表了UTHSCSA牙科，医学和研究生院的最佳导师，并因他们对颅面口腔生物学研究的共同兴趣而联合起来。因此，COSTAR为一个特殊的多学科和跨学科的研究和培训环境提供了强有力的机构联系，进一步加强了颅面口腔生物学研究的机构基础设施。被选中参加COSTAR项目研究培训的高度积极和敬业的学生和研究员将参加一系列COSTAR核心课程和经验，这些课程和经验与牙科学院和整个校园的项目相结合。重要的是，costar赞助的活动在受训者之间产生了强烈的规划认同、协作和网络。成功提交个人奖项申请，将鼓励学员在独立研究和学术研究方面取得成功。通过正式制定跟踪和分析计划，专注于不断改进我们的培训计划，COSTAR领导委员会和咨询委员会为颅面口腔生物学新科学家的研究培训提供了最佳环境，延续了我们在UTHSCSA前学员学术界的长期成功传统。

DESCRIPTION (provided by applicant): This application is for renewal of the T32 comprehensive institutional research training grant COSTAR (Craniofacial Oral-Biology Student Training in Academic Research). Building on longstanding institutional research training experience, COSTAR has trained 14 DDS/PhD students, 24 PhD students, 17 Post-doctoral Fellows, 4 faculty fellows, and 93 summer dental student research fellows since first funded in 2002. Our outcome measures since 2002 indicate an outstanding training environment, as documented by publication of 270 peer reviewed papers by trainees, including Nature and PNAS, and 19 trainees (35%) receiving and transferring to individual NIH awards (F30, F31, F32, K08, K23, or R21) or equivalent fellowships. Our tracking of former advanced degree COSTAR trainees, graduates, and fellows shows an exemplary rate (82%) of retention in research settings, including academic or scientist positions or continued postdoctoral research training. The COSTAR program has made great strides in promoting diversity with recruitment of 44% underrepresented minority and 73% women trainees. Based upon these objective measures of success and our continual self-assessment process, we propose a renewal for an additional five year period of support. Our focused goal remains devoted to train a cadre of highly skilled, interactive scientists who can successfully address the new opportunities in dental, oral, and craniofacial research and become a part of the future academic faculty in US dental schools. The COSTAR program will offer three integrated training tracks: 1) DDS/PhD program, 2) PhD program, and 3) Basic or Clinical-translational Postdoctoral research fellowships. These three training tracks are provided in three integrated thematic areas by a highly selected, research intensive, and collaborative, Program Faculty representing the best mentors across the Dental, Medical, and Graduate Schools at UTHSCSA, and united by their shared interest in Craniofacial Oral Biology research. Thus, COSTAR serves as a strong institutional nexus for an exceptional multi- and inter-disciplinary research and training environment further enhancing the institutional infrastructure for research in Craniofacial Oral Biology. Highly motivated and dedicated students and fellows who are selected for research training in the COSTAR program will participate in a series of COSTAR core courses and experiences that are integrated with programs across the Dental School and the campus at large. Importantly, COSTAR-sponsored activities yield a strong programmatic identity, collaboration, and networking among trainees. Trainee development towards research independence and future success in academic research will be encouraged by successful submission of applications for individual awards. By formally developing a tracking and analyzing plan focused on continuously improving our training program, the COSTAR Leadership Council and Advisory Boards provide an optimal environment for research training of new scientists in Craniofacial Oral Biology following the tradition of our long-term success in academia of former trainees at the UTHSCSA.