AVERT-DOSE (Determining Optimal early rehabilitation after StrokE): A multi-arm covariate-adjusted, response-adaptive randomised controlled trial

AVERT-DOSE是一项国际性的、研究者主导的临床试验，在澳大利亚开发，但招募了来自全球6个国家的2500名患者。在本试验中，我们将建立急性脑卒中患者早期活动能力康复的最佳模型。我们制定的方案将适用于发达国家和发展中国家的临床实践，并有助于减少世界范围内卒中相关残疾的不可接受的高个人和社区负担。

AVERT-DOSE is an international, investigator-led clinical trial, developed in Australia but recruiting >2500 patients from 6 countries around the world. In this trial we will establish the optimal model of early mobility rehabilitation for people with acute stroke. The protocols we develop will be suitable for adoption in clinical practice in developed and developing countries and help reduce the unacceptably high personal and community burden of stroke-related disability world wide.