Optimising upper limb recovery following stroke: A randomised controlled trial of the effects of botulinum toxin-A combined with intensive rehabilitation compared to botulinum toxin-A alone

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The devastating loss of movement in the hand after stroke could potentially be addressed, but we currently lack of research investigating treatment interventions. This randomised controlled trial will compare the routine interventions of botulinum toxin to botulinum toxin plus best-practice therapy for both cost and clinical outcome. Findings from this trial will provide the necessary information to make decisions about what will improve spasticity and function in the hand and arm after stroke.