Multidisciplinary Schizophrenia Research Training

 描述（由申请人提供）：这是马里兰州精神病学研究中心（MPRC）T32培训补助金的第二次竞争性更新，最初于2003年资助（MH 067533）。拟议计划的目标是准备医学博士，博士和药学博士感兴趣的基础或临床研究的职业生涯在精神分裂症相关疾病的转化研究。MPRC是马里兰州大学医学院和精神病学系的一个有组织的研究中心，是一个专注于精神分裂症和相关疾病研究的中心，位于斯普林格罗夫医院中心，这是一个位于巴尔的摩外的马里兰州住院精神卫生设施。MPRC的教师有一个临床和神经科学研究的综合研究计划，涉及神经影像学，神经生理学，生物化学，啮齿动物模型，病因，症状，内在表型，神经认知，精神病理学领域和与精神分裂症和相关疾病相关的特定病理学的实验疗法。所有教师都获得了有竞争力的研究资金，MPRC和综合协作框架25年来一直支持NIMH P50奖项，包括刚刚完成的CIDAR和刚刚资助的Conte中心。MPRC的特点是临床前和临床研究者之间的频繁互动和合作。这种背景准备教师在MPRC采取积极的作用，支持NIMH研讨会开发行为结构的RDoC倡议。科学的机会和合作是丰富的广泛参与与医学的马里兰州和药学院在附近的马里兰州巴尔的摩大学的其他组成部分。在这个T32奖学金下提供的博士后培训主要集中在基础神经科学和精神分裂症及相关疾病的临床研究。所有学员都接受了MPRC的翻译观点的教育，并提供了临床和神经科学方面的导师和教学培训。这一竞争性五年期续延申请的续延提议每年继续资助5个职位，每个职位的研究金持续2-3年。这个T32计划在招聘和培训博士后研究员的科学生涯方面是成功的，包括临床科学家。该计划的毕业生领导生产，成功的研究密集型职业。进度报告提供了关于毕业生和目前研究员的详细情况。

 DESCRIPTION (provided by applicant): This is the second competitive renewal of a T32 training grant at the Maryland Psychiatric Research Center (MPRC), originally funded in 2003 (MH067533). The goal of the proposed program is to prepare MDs, PhDs and PharmDs interested in basic or clinical research for a career in translational research in schizophrenia related disorders. The MPRC, an Organized Research Center of the University of Maryland School of Medicine and division of the Department of Psychiatry, is a focused center for research on schizophrenia and related disorders, located on the grounds of the Spring Grove Hospital Center, a State of Maryland inpatient mental health facility located just outside Baltimore. Faculty at the MPRC have an integrated research program of clinical and neuroscience research involving neuroimaging, neurophysiology, biochemistry, rodent models, etiologic factors, symptoms, endophenotypes, neurocognition, domains of psychopathology and experimental therapeutics for specific pathologies associated with schizophrenia and related disorders. All faculty are successful with competitive research funding and the MPRC and the integrated and collaborative framework has supported NIMH P50 awards for over 25 years including a just completed CIDAR and just funded Conte centers. The MPRC is characterized by frequent interaction and collaboration among preclinical and clinical investigators. This background prepared faculty at MPRC to take an active role in supporting NIMH workshops developing behavioral constructs for the RDoC initiative. Scientific opportunities and collaborations are enriched with extensive involvement with other components of the University of Maryland School of Medicine and School of Pharmacy at the nearby University of Maryland Baltimore. Postdoctoral training offered under this T32 fellowship has a primary focus on both basic neuroscience and clinical investigations of schizophrenia and related disorders. All trainees are educated on the translational perspective of the MPRC and provided mentors and didactic training in both clinical and neuroscience. This renewal for a competitive five- year renewal application proposes to continue funding 5 positions a year with each a fellowship lasting for 2-3 years. This T32 program is successful in terms of recruiting and training post-doctoral fellows for a scientific career including clinician scientists. Graduates of the program lead productive, successful research-intensive careers. Details on graduates and the present fellows are provided in the progress report.