2017 Chronobiology Gordon Research Conference & Gordon Research Seminar

项目摘要 我们请求部分支持第20届时间生物学戈登研究会议（GRC）和 伴随着第三次戈登研究研讨会（GRS），这将在斯托弗莱克会议中心举行， 佛蒙特州从2017年7月15日至7月21日。从NIH收到的资金将用于支持注册费 和/或旅行费用的GRC和GRS参与者，特别是博士后研究员和研究生。的 会议将集中在时间生物学的关键研究领域-一个非常跨学科的领域， 越来越多地吸引了来自许多不同研究领域的科学家，包括神经科学，睡眠，新陈代谢和 他使用了从分子遗传学到理论生物学的方法。鉴于其对大脑的强调 调节行为和生理的昼夜节律回路，生物钟与代谢因素的相互作用， 昼夜节律调节与衰老以及与年龄相关的神经系统疾病的相关性， 与NINDS、NIA和NIDDK的特派团合作）。会议的副主题是"跨性别的昼夜节律调节"。 生理系统，寿命和病理条件"，不仅强调多样性的整合 研究领域和生物体，而且越来越多地认识到生物钟的重要性， 健康和疾病。所有发言者和讨论领导人都在科学的前沿工作， 与我们领域的知名人士协商，代表了时间生物学研究的广度， 一个非常高质量的节目。（在选择发言人的过程中）给予了特别注意， （在登记过程中）考虑到文化多样性、性别平衡以及纳入即将到来的 年轻的科学家培训将进一步纳入该计划（i）通过第三次全球遥感 时间;（ii）根据提交的摘要，为学生和博士后研究员安排8个额外的简短演讲 及（iii）为学员提供与资深研究员讨论的机会。的 2017年会议的具体目标是： 1.提供一个自由的论坛，不受阻碍地讨论最新的（未发表的）时间生物学研究。这 会议将为实现这一目标采取若干措施。 2.汇集来自不同研究水平的科学家，从时间生物学的分子方面， 生理和生物节律的转化研究，突出了生物钟的重要性， 健康和疾病。预计后者将得到行业代表的帮助。 3.确定未来研究的优先主题（例如，昼夜节律调节对神经疾病的影响，衰老， 和新陈代谢）通过公开辩论知识差距，特别是争议。 4.通过提供高质量的培训，不断促进学员和高级研究人员之间的互动， 为处于不同职业阶段的科学家提供了一个可进入的竞技场。我们还采取具体步骤， 鼓励学员参与讨论，并为他们提供方便的教师。

Project Summary We request partial support for the 20th Chronobiology Gordon Research Conference (GRC) and the accompanying 3rd Gordon Research Seminar (GRS), which will be held at Stoweflake Conference Center, Vermont from July 15th to July 21st, 2017. Funds received from the NIH will be used to support registration fees and/or travel costs for GRC and GRS participants, especially postdoctoral fellows and graduate students. The conference will focus on key research areas in chronobiology - a very interdisciplinary field that continuously and increasingly attracts scientists from many diverse research areas including neuroscience, sleep, metabolism and aging and uses approaches ranging from molecular genetics to theoretical biology. Given its emphasis on brain circadian circuits that regulate behavior and physiology, the interactions of clocks with metabolic factors, and the relevance of circadian regulation for aging as well as for age-related neurological disorders, the conference fits with the missions of NINDS, NIA and NIDDK). The subtheme of the conference is “Circadian regulation across physiological systems, lifespan and pathological conditions” emphasizing not only the integration of diverse research fields and organisms, but also the increasingly recognized critical importance of circadian clocks for health and disease. All speakers and discussion leaders work at the forefront of science and have been selected in consultation with renowned figures in our field representing the breadth of chronobiology research, leading to an extremely high-quality program. Special attention has been given (in the speaker selection process) and will be given (in the registration process) to cultural diversity, gender balance as well as to incorporating upcoming young scientists. Training will be further integrated in the program (i) through the GRS taking place for the third time; (ii) assigning eight additional short talks to students and postdoctoral fellows based on submitted abstracts and (iii) providing many opportunities for trainees to be involved in discussions with senior researchers. The specific objectives of the 2017 conference are: 1. To provide a forum for free, unhampered discussion of the latest (unpublished) chronobiology research. This conference will feature several measures towards this objective. 2. To bring together scientists from diverse research levels, ranging from molecular aspects of chronobiology to physiological and organismal rhythms to translational studies highlighting the importance of circadian clocks for health and disease. The latter will be helped by industry representatives, who are expected. 3. To identify priority themes for future research (e.g. impact of circadian regulation on neural disorders, aging, and metabolism) by openly debating knowledge gaps and especially controversies. 4. To continuously foster interactions between trainees and senior researchers by providing a high-quality and accessible arena for scientists at very different stages of their careers. We are also taking specific steps to encourage participation of trainees in Discussions, and to provide them with ready access to faculty.