Stand and Move at Work: A Group-Randomized Trial

 描述(申请人提供)：中等强度的体育锻炼对健康的益处在一生中都是公认的，并且正在取得进展，以帮助美国人达到2008年美国人每周150分钟的中等强度体育锻炼的指导方针。然而，体力活动指南也指出，有必要“最大限度地减少长时间久坐不动的时间”；然而，成年人每天平均有7.5小时久坐不动(即坐着)。我们的初步研究表明，将每天从久坐不动的体力活动调整为轻强度的体力活动，保持中等强度的体力活动不变，可以显著降低健康风险。考虑到美国员工每天有70%-80%的时间坐在办公桌前，工作场所是减少久坐行为的理想环境。事实上，我们的初步研究表明，可以在不干扰日常工作和生产力的情况下，实现姿势和光强度体力活动的微小但累积的变化。减少坐着和增加工作场所光强度体力活动的策略一直很有前景，但受到样本量小、持续时间短和非随机设计的限制。该项目旨在两个州的24个工作场所(N=720名工人)测试两种干预措施的相对有效性。运动干预是一种多层次的个人、社会、环境和组织干预，旨在增加工作场所的轻强度体力活动。站立和移动干预是在安装和使用坐立工作站以减少坐着和增强光强度体力活动机会的基础上进行的移动干预。我们的主要结果将是客观地测量光强度体力活动和静坐12个月的变化，6个月的额外过程措施和24个月的长期可持续结果。我们的次要结果将是心脏代谢风险，使用同一时间点上的空腹血糖、胰岛素、甘油三酯、高密度脂蛋白-胆固醇和血压的综合测量。这一应用程序的独特功能是分组随机设计，据我们所知，该设计尚未用于测试坐-立工作站在成人劳动力中的有效性，对工作场所姿势和活动的精确测量，两个州(亚利桑那州和明尼苏达州)的地理和工作场所多样性，由运动生理学家、健康专业人员、流行病学家和生物统计学家组成的多样化研究团队，以及由于真实的词语设置和高水平的普适性，立即传播和广泛实施的强大潜力。该项目将是迄今为止关于多层次工作场所干预以增加光强度体力活动的有效性和有效性的最明确的研究， 减少久坐，改善心脏代谢健康。

 DESCRIPTION (provided by applicant): The health benefits of moderate-vigorous physical activity are well-established across the lifespan and progress is being made to help Americans achieve the 2008 Physical Activity Guidelines for Americans of 150 minutes/week of moderate-vigorous physical activity. However, Physical Activity Guidelines also state the need to "minimize the amount of time spent being sedentary for extended periods"; yet adults spend an average of 7.5 h/day being sedentary (i.e., sitting). Our preliminary studies suggest reallocating just 30 min/day from sedentary to light-intensity physical activity, holding moderate-vigorous physical activity constant, can significantly improve health risks. The workplace is the ideal context to reduce sedentary behavior given that American workers spend 70-80% of their workday sitting at a desk. Indeed, our preliminary studies suggest that small but cumulative changes in posture and light-intensity physical activity can be achieved without interfering with daily tasks and productivity. Strategies to reduce sitting and increase light-intensity physical activity in the workplace have been promising but are limited by small sample size, short duration, and non- randomized designs. This project aims to test the relative efficacy of two interventions in 24 worksites across two states (N=720 workers). The MOVE intervention is a multilevel individual, social, environmental, and organizational intervention targeting increases i light-intensity physical activity in the workplace. The STAND&MOVE intervention is the MOVE intervention in addition to the installation and use of sit-stand workstations to reduce sitting an enhance light-intensity physical activity opportunities. Our primary outcome will be objectively-measured changes in light-intensity physical activity and sitting over 12 months, with additional process measures at 6 months and longer-term sustainability outcomes at 24 months. Our secondary outcome will be cardiometabolic risk using a composite measure of fasting glucose, insulin, triglycerides, HDL-cholesterol, and blood pressure over the same time points. Unique features of this application are the group-randomized design, which to our knowledge has yet to be used to test the efficacy of sit-stand workstations in the adult workforce, precise measurement of workplace posture and activity, geographical and workplace diversity across two states (Arizona and Minnesota), diverse investigator team of exercise physiologists, wellness professionals, epidemiologists, and biostatisticians, and strong potential for immediate dissemination and broad implementation due to the real-word setting and high level of generalizability. This project stands to be the most definitive study to date on the efficacy and effectiveness of multi-level workplace interventions to increase light-intensity physical activity, reduce sitting, and improve cardiometabolic health.