Vermont Genetics Network-Vermont INBRE

 描述(由申请人提供)：佛蒙特州IDEA卓越生物医学研究网络(INBRE)的续签申请的总体目标是利用我们十年来建立的网络(佛蒙特州遗传学网络(VGN))，并提高佛蒙特州的生物医学研究能力和竞争力。我们在领先的机构佛蒙特州大学(UVM)创建了一流的设施来服务于网络；通过研究奖励和指导促进了VGN学士学位合作机构(BPI)的教职员工和学生的研究；为BPIs和其他学院提供了课程模块，让学生能够亲身体验研究方案并使用VGN的设施。评估显示，VGN资助的BPI和UVM的教职员工正在出版，并变得具有竞争力。自2001年以来，曾由VGN资助的密歇根大学教职员工和BPI教职员工中有32%的人获得了校外资助。VGN学生正在进入生物医学领域：自2001年以来，81%的受资助本科生已经毕业，其中87%在STEM领域从事职业或培训，51.4%在健康相关专业，其中大部分是医生。这些设施为资助研究和学生培训提供服务，并为拨款申请收集关键数据。VGN有三个新的具体目标：1.实施一项新的计划，以提高网络教师的资金竞争力；2.扩大本科生实习计划，增加多样化的培训环境和参与学生的多样性，特别是退伍军人、残疾人和代表性不足的少数族裔；3.增强蛋白质组学和微阵列服务，并实施可持续发展的商业计划。新的专业发展和教育核心将落实目标1和目标2：促进指导和为教师竞争力提供资源，包括为教师和学生举办定制研讨会，以培养他们的技能和改进课程，并扩大学生多样性和实习选择。生物信息学核心将为VGN设施提供关键的数据分析支持；协助网络教员进行研究并将研究纳入课堂；支持网络通信和数据管理的网络基础设施。行政核心将提供后勤、财务、合规监督和外部评价，以确保这个由不同伙伴组成的网络对网络机构不断变化的需求和不断发展的实力敏感。行政核心安排指导和本科生实习生计划，以通过PDE核心增加生物医学劳动力的规模和多样性。VGN将继续开发共享的研究资源，如VGN/ABRF可搜索数据库。虽然主题遗传学允许在UVM和BPI广泛纳入生物医学研究，但我们提出了一个新的副主题--人类健康和行为，以允许BPI更多地参与。VGN得到了所有网络机构的大力支持和承诺，以及区域INBRE和Cobres之间的合作。为了促进研究文化，两个BPI将翻新教职员工和学生研究的空间。

 DESCRIPTION (provided by applicant): The overall goal of this renewal application for the Vermont IDeA Network of Biomedical Research Excellence (INBRE) is to capitalize upon the network that we have built over a decade (the Vermont Genetics Network (VGN)), and to increase biomedical research capacity and competitiveness in Vermont. We have created state-of-the art facilities at the University of Vermont (UVM), the lead institution, to serve the networ; promoted faculty and student research at VGN Baccalaureate Partner Institutions (BPIs) with research awards and mentoring; provided BPIs and other colleges with class modules for students to have hands-on experience with research protocols and use VGN's facilities. Assessments show that VGN funded faculty at BPIs and UVM are publishing and becoming competitive. Since 2001, 64% of the UVM faculty and 32% of the BPI faculty once supported by VGN have received extramural funding. VGN students are entering biomedical fields: Since 2001, 81% of supported undergraduates have already graduated and of those 87% are in careers or training in STEM fields, 51.4% in health related professions with the majority of these as physicians. The facilities provide service to funded research and student training, and collect critical data for grant applications. Three new specific aims build upon successes and bring innovation to VGN: 1. Implement a new program to increase funding competitiveness of network faculty; 2. Expand the undergraduate internship program to add a variety of training settings and diversity of participating students particularly veterans, disabled and under-represented minorities; 3. Enhance Proteomics and Microarray services and implement sustainability business plans. The new Professional Development and Education Core will implement Aims 1 and 2: facilitate mentoring and provide resources for faculty competitiveness including custom workshops for faculty and students to build their skills and enhance curriculum, and broaden student diversity and options for internships. The Bioinformatics Core will provide critical data analysis support for the VGN facilities; give assistance to network faculty for research and incorporation of research into classes; and support cyber infrastructure for network communication and data management. The Administrative Core will provide logistical, financial, compliance oversight, and external evaluation to ensure that this network of diverse partners is sensitive to changing needs and evolving strengths of the network institutions. The Administrative Core arranges mentoring and undergraduate intern programs to increase the biomedical workforce size and diversity through the PDE Core. VGN will continue to develop shared research resources such as the VGN/ABRF searchable database. While the theme Genetics allows for broad inclusion of biomedical research at UVM and BPIs, we propose a new sub-theme of Human Health and Behavior to allow for greater participation at BPIs. VGN has strong support and commitments from all network institutions and collaborations among regional INBREs and COBREs. To promote a culture of research, two BPIs will renovate space for faculty and student research.