The Brown Initiative in HIV and AIDS Clinical Research for Minority Communities

描述(由申请人提供)：本提案是布朗弱势社区艾滋病临床研究项目的竞争性续签申请，目前由NIMH R25MH083620资助。我们的目标是培训下一代少数群体研究人员，以应对艾滋病毒预防、诊断和治疗方面的挑战，特别是在少数群体社区。近50%的新感染病例发生在非洲裔美国人中，在艾滋病毒/艾滋病的诊断和护理连续过程中，非洲裔美国人的健康状况在各个方面都较差。特别是，非洲裔美国人社区，特别是市中心的东海岸以及南部农村和城市，受艾滋病毒/艾滋病的影响最大。奥巴马总统的国家艾滋病战略呼吁减少艾滋病毒发病率，减少艾滋病毒感染的种族差异，并将资源分配给受影响最严重的社区。为了解决艾滋病毒感染方面的种族差异和艾滋病毒/艾滋病对少数群体社区的影响，我们必须培训来自受影响最严重社区的少数群体调查员，特别是来自市中心社区和美国南部的少数群体调查员。这需要对下一代艾滋病毒/艾滋病研究人员进行跨学科、有文化能力的研究培训；这种培训必须解决导致这一流行病的社会、结构和行为因素。布朗弱势社区艾滋病毒和艾滋病临床研究计划是一项针对来自代表性不足的种族和民族群体的新调查人员的教育和指导计划，特别关注非裔美国人对艾滋病毒/艾滋病健康差距以及监禁、丙型肝炎合并感染、药物使用和精神疾病等共同流行的研究。在我们的头五年里，我们培训了28名少数民族博士后和初级教员进行与艾滋病毒相关的临床研究，并与五所大学发展了合作关系，重点是密西西比州和南部。来自不同学科的学者代表14个机构；79%的学者是非洲裔美国人，11%是亚太岛民，7%是西班牙裔，3%是美洲原住民。这项建议包括更加注重社区参与的研究。我们的目标是培训下一批调查人员进行跨学科研究，以应对 在美国受影响最严重的社区，特别是在南部和市中心，造成艾滋病毒感染种族差异的社会、行为和结构因素。我们通过摘要、手稿、独立拨款、教师职位和有意义地参与社区参与的研究来衡量我们倡议的成功。

DESCRIPTION (provided by applicant): This proposal is a competitive renewal application for The Brown Initiative in HIV and AIDS Clinical Research for Disadvantaged Communities, currently funded through NIMH R25MH083620. Our goal is to train the next generation of minority researchers to address the challenges of prevention, diagnosis and treatment of HIV, particularly in minority communities. Nearly 50% of new infections are among African-Americans, and African-Americans have poorer health outcomes at every point along the HIV/AIDS continuum of diagnosis and care. In particular, African American communities, particularly the inner-city Eastern seaboard and the rural and urban South, are most heavily impacted by HIV/AIDS. President Obama's National AIDS Strategy calls for reduction in HIV incidence, reductions in racial disparities in HIV infection, and allocating resources to the most heavily impacted communities. In order to address racial disparities in HIV infection and the impact of HIV/AIDS in minority communities, we must train minority investigators from the most heavily impacted communities, particularly from inner city communities and the American South. This requires interdisciplinary, culturally competent research training of the next generation of HIV/AIDS researchers; this training must address the social, structural and behavioral factors contributing to the epidemic. The Brown Initiative in HIV and AIDS Clinical Research for Disadvantaged Communities is an educational and mentoring program for new investigators from underrepresented racial and ethnic groups, with a particular focus on African Americans conducting research on HIV/AIDS health disparities and the co-occurring epidemics of incarceration, hepatitis C co-infection, substance use, and mental illness. During our first five years, we trained 28 minority postdoctoral and junior faculty members in HIV related clinical research, and developed collaborative relationships with five universities, with an emphasis on Mississippi and the South. Scholars from diverse disciplines represent 14 institutions; 79% of scholars are African- American, 11% are Asian Pacific Islander, 7% are Hispanic, and 3% are Native American. This proposal includes a stronger focus on community-engaged research. We aim to train the next cadre of investigators to conduct interdisciplinary research that responds to the social, behavioral and structural factors that contribute to racial disparities in HIV infectio in the most heavily impacted communities of the US, particularly in the South and in inner city settings. We gauge success of our initiative through abstracts, manuscripts, independent grant funding, faculty positions, and meaningful participation in community-engaged research.