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中文摘要
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描述(由申请人提供):埃默里神经紧急情况治疗试验-东南合作(NETT-SEC)是NETT网络的一个富有成效的成员。NETT-SEC参加了所有NETT试验,在Rampart、Alias和Protect III的登记人数中排名前三分之一,有148多名受试者参加了NETT试验(截至2011年11月14日)。NETT-SEC的目标与NETT的总体目标是同步的:在广泛的神经紧急情况下进行大型简化的第三阶段临床试验,以降低神经疾病的发病率和死亡率。我们参与了NETT的所有研究,并贡献了来自所有种族和民族的儿科和成人受试者。NETT-SEC已与急诊医学、神经病学、神经重症监护、介入神经放射学、放射学、神经外科、麻醉学、创伤外科、药理学、伦理学、生物医学工程、实验室科学、神经心理学、神经眼科学、整形外科(脊柱)、EMS、工业(Banyan Biomarkers)等形成了广泛和高度功能的合作。此外,NETT-SEC汇集了一系列大容量的城市和郊区医院,这些医院在多种族地区进行突破性的神经急救研究方面拥有良好的专业知识和经验。目标:1.继续在NETT赞助的临床试验中招募不同的受试者;2.通过扩大合作、培训计划、学生和教职员工指导以及社区推广,发展NETT-SEC;3.通过加强NETT的运作、扩大NETT的研究组合、促进研究伦理对话和向社区传播发现,促进神经紧急情况研究。NETT-SEC作为第一个NETT网络的生产性枢纽,有着良好的业绩记录,并将继续通过开展高质量、高效率的工作来支持NETT和NINDS的目标。学术和社区环境中的第三阶段临床试验。
英文摘要
DESCRIPTION (provided by applicant): The Emory Neurological Emergencies Treatment Trials - Southeastern Collaborative (NETT-SEC) is a productive member of the NETT network. The NETT-SEC has participated in all NETT trials and is in the top 1/3rd for enrollments in RAMPART, ALIAS, and ProTECT III, accounting for over 148 subjects enrolled into the NETT trials (as of 11/14/2011). The goal of the NETT-SEC is synchronous with the NETT's overall stated purpose: to conduct large streamlined phase III clinical trials in a broad spectrum of neurological emergencies in order to reduce the morbidity and mortality of neurological diseases. We have participated in all of the NETT studies and contributed pediatric and adult subjects from all races and ethnicities. The NETT-SEC has formed extensive and highly functional collaborations with emergency medicine, neurology, neurointensive care, interventional neuroradiology, radiology, neurosurgery, anesthesiology, trauma surgery, pharmacology, ethics, biomedical engineering, laboratory science, neuropsychology, neuro-ophthamology, orthopedics (spine), EMS, Industry (Banyan Biomarkers), and others. In addition, the NETT-SEC brings together an extensive array of high volume urban and suburban hospitals with a well-established track record of expertise and experience in conducting ground-breaking research in neurological emergencies in a multiracial region. AIMS: 1.Continue high enrollment of a diverse population of subjects in NETT-sponsored Clinical Trials; 2. Grow the NETT-SEC by expanding collaborations, training programs, student and faculty mentoring, and community outreach; 3. Facilitate neurological emergencies research by enhancing NETT operations, expanding the NETT research portfolio, contributing to the dialog on research ethics, and disseminating discoveries to the community. The NETT-SEC has a proven track record as a productive hub of the first NETT network and will continue to support the goals of the NETT and NINDS by conducting high quality, efficient. Phase III clinical trials in both academic and community settings.
期刊论文(5)
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会议论文
Impact of individual clinical outcomes on trial participants' perspectives on enrollment in emergency research without consent.
个体临床结果对试验参与者在未经同意的情况下参加紧急研究的看法的影响。
DOI: 10.1177/1740774516677276
发表时间: 2017
期刊: Clinical trials (London, England)
影响因子: --
作者: [Whitesides,LouisaW, Baren,JillM, Biros,MichelleH, Fleischman,RossJ, Govindarajan,PrasanthiR, Jones,ElizabethB, Pancioli,ArthurM, Pentz,RebeccaD, Scicluna,VictoriaM, Wright,DavidW, Dickert,NealW]
通讯作者: Dickert,NealW
DOI: 10.1080/23294515.2017.1308978
发表时间: 2017-04-01
期刊: AJOB empirical bioethics
影响因子: --
作者: [Scicluna, Victoria M, Ali, Mohammed K, Dickert, Neal W]
通讯作者: Dickert, Neal W
ProTECT III
  • 批准号:
    8323400
  • 项目类别:
  • 资助金额:
    $638.62万
  • 财政年份:
    2009
  • 负责人:
    DAVID W WRIGHT
  • 依托单位:
ProTECT III
  • 批准号:
    8499434
  • 项目类别:
  • 资助金额:
    $50.85万
  • 财政年份:
    2009
  • 负责人:
    DAVID W WRIGHT
  • 依托单位:
ProTECT III
  • 批准号:
    7878810
  • 项目类别:
  • 资助金额:
    $886.71万
  • 财政年份:
    2009
  • 负责人:
    DAVID W WRIGHT
  • 依托单位:
ProTECT III
  • 批准号:
    8113157
  • 项目类别:
  • 资助金额:
    $833.03万
  • 财政年份:
    2009
  • 负责人:
    DAVID W WRIGHT
  • 依托单位:
海外基金