2018 Proteoglycans Gordon Research Conference and Gordon Research Seminar

项目总结/摘要 蛋白聚糖戈登研究会议（GRC）是一个订阅量很大的会议， 口径未发表的数据，从外地领导人，并提供了一个非常合议的气氛，促进合作。 该会议自1984年以来每两年举行一次，享有盛誉。当前的应用程序 正在请求对下一次会议的部分支持，“蛋白聚糖在稳态和疾病：破解 PG代码”，这将于2018年7月8日至13日在普罗克特学院，安多弗，新罕布什尔州举行。计划中的会议 该计划由科学组织委员会选出的特邀演讲者组成，该委员会包括前 蛋白聚糖GRC主席，由在这一广泛领域具有丰富专业知识的其他研究者提供意见 研究领域。除了汇集了高度成就，著名的蛋白聚糖研究科学家， 他们中的一些人以前没有参加过这个GRC，会议提供了一个论坛， 调查人员在海报会议和简短的谈话中介绍他们的工作，后者被选为 与会议主题相辅相成。我们的目标是该计划将涵盖最前沿的最新研究 在我们的社区内提供职业发展的机会。 延长的讨论时间，集体用餐和社交活动为与会者提供了充分的机会来讨论 在蛋白聚糖领域的分支中的特定“最新技术状态”，学习新的研究工具，并建立 新的合作…在2018年的会议上，将报道蛋白聚糖在蛋白质合成中的作用。 骨、肌肉、肌腱和椎间盘的发育、稳态和病理。其他高主题 与肌肉骨骼研究的相关性将包括在内，如衰老，自噬，细胞信号传导，纤维化， 炎症、代谢和氧化应激。这些领域也将在癌症的背景下讨论， 心血管疾病、宿主-病原体相互作用、溶酶体贮积症和神经元生物学。的 会议还将介绍新开发的蛋白聚糖研究工具和技术， 蛋白聚糖作为治疗剂和组织工程方法的发展。 蛋白聚糖GRC力求具有包容性，通常在男性和女性中实现近乎平等的平衡 代表和展示来自世界各地的科学家。与会者将通过邀请或从 在线提交的申请将被选择，包括一组不同的研究人员。中附加地 2018年，我们将增加一个Power Hour，讨论科学生涯中存在的性别问题/障碍 发展

Project Summary / Abstract The Gordon Research Conference (GRC) on Proteoglycans is a well-subscribed meeting that presents high caliber unpublished data from field leaders and provides a very collegial atmosphere that fosters collaboration. The conference has been held biennially since 1984 and has an outstanding reputation. This current application is requesting partial support for the next conference, “Proteoglycans in Homeostasis and Disease: Cracking the PG Code”, which will be held during July 8-13, 2018 at Proctor Academy, Andover, NH. The planned conference program is composed of invited speakers chosen by a scientific organizing committee that includes former Proteoglycan GRC Chairs with input from other investigators who have substantial expertise across this broad research area. In addition to bringing together highly accomplished, renowned proteoglycan research scientists, some of whom will have not attended this GRC previously, the conference provides a forum for early stage investigators to present their work in poster sessions and short talks, where the latter are selected to be complementary to the session themes. Our aim is that the program will cover the latest research at the forefront of the proteoglycan field and provide opportunities for career development within our community. The extended discussion times, group meals and social events give attendees ample opportunity to discuss the specific ‘state of the art’ within their branch of the proteoglycan field, learn of novel research tools, and establish new collaborations.. At the 2018 conference, there will be coverage of the role of proteoglycans in the development, homeostasis and pathology of bone, muscle, tendon and intervertebral disc. Other topics of high relevance to musculoskeletal research will be included, such as aging, autophagy, cell signaling, fibrosis, inflammation, metabolism and oxidative stress. These areas will also be discussed in the contexts of cancer, cardiovascular disease, host-pathogen interactions, lysosomal storage disorders and neuronal biology. The conference will additionally feature newly developed tools and technologies for proteoglycan research, and the development of proteoglycans as therapeutics and in tissue engineering approaches. The Proteoglycan GRC strives to be inclusive, typically achieving a near equal balance of male and female delegates and showcasing scientists from throughout the world.. Attendees will be selected by invitation or from the applications submitted online and will be chosen to comprise a diverse set of researchers, . Additionally in 2018 we will add a Power Hour for discussion of gender issues/ impediments that exist in scientific career development.