The Health ePeople Resource for Mobilized Research

行政核心--项目摘要/摘要 我们寻求创建Health ePeople资源，这是一个灵活、易于访问和可靠的基础设施，以 开展移动健康研究。这项工作将建立在目前的健康电子心脏研究基础上，这是一项基于互联网的临床研究 这个研究平台已经招募了来自世界各地的20,000多名参与者。虽然 最初开发用于研究心血管疾病的Health eHeart被来自多个领域的研究人员使用， 并帮助我们启动当前RFA中规定的许多目标。我们已经成功地实施了 构建了用户友好的界面，用于收集患者报告的结果、经过验证的调查数据以及与 多个传感器、设备和应用程序；我们拥有IRB批准的系统，使用模块化电子同意； 我们有超过20,000名深度参与的参与者有兴趣为移动健康研究做出贡献；我们有 制定方法，使外部调查人员能够以可定制的方式利用和招募他们自己的参与者； 我们开发了一个研究管理门户(包括实时仪表板和参与者特征- 基于过滤系统)和可供外部调查人员使用的灵活消息传递系统；我们有 建立了一个数据库和数据管理系统，旨在坚持最高标准的隐私， 安全性和可靠性；我们对该平台进行了迭代和调整，以利用新兴的 技术和尖端方法。在这些优势的基础上，我们准备充分利用 该奖项提供的机会，将Health eHeart研究转变为一般Health ePeople 资源。行政核心将由管理卫生保健的人员基础设施组成 EPeople资源，并将为来自学术界的非营利性研究人员提供行政支持 组织、政府机构和行业使用健康电子人资源进行研究。 行政核心将提供行政基础设施，以确保数据安全和隐私 与各种合作者、移动健康产品和研究设计合作。行政核心意志 负责为Health ePeople开发和管理可持续的财务模式 资源。最后，行政核心将提供行政基础设施来管理公众 知识的关系、营销、沟通和传播。

ADMINISTRATIVE CORE— PROJECT SUMMARY/ABSTRACT We seek to create the Health ePeople Resource, a nimble, readily-accessible, and reliable infrastructure to conduct mHealth research. This effort will build on the current Health eHeart Study, an internet-based clinical research platform that has enrolled more than 20,000 engaged participants from around the world. Although initially developed to study cardiovascular disease, Health eHeart is in use by investigators from multiple fields, and helps us jumpstart many of the objectives set out in the current RFA. We have successfully implemented a user-friendly interface built to collect patient-reported outcomes, validated survey data, and integrations with multiple sensors, devices, and apps; we have an IRB approved system using modular electronic consenting; we have over 20,000 deeply involved participants interested in contributing to mHealth research; we have developed ways for external investigators to utilize and enroll their own participants in a customizable fashion; we have developed a study management portal (including a real-time dashboard and participant characteristic- based filtering system) and a flexible messaging system that can be utilized by external investigators; we have built a database and data management system constructed to adhere to the highest standards of privacy, security, and reliability; and we have iterated and adapted the platform to take advantage of emerging technology and cutting-edge methods. Building from these strengths, we are ready to fully leverage the opportunities afforded by this award, transforming the Health eHeart Study into a general Health ePeople Resource. The Administrative Core will be comprised of the personnel infrastructure to manage the Health ePeople Resource and will provide the administrative support for investigators from academia, nonprofit organizations, governmental agencies and industry to conduct research using the Health ePeople Resource. The Administrative Core will provide the administrative infrastructure to ensure data security and privacy in working with a variety of collaborators, mHealth products, and research designs. The Administrative Core will be responsible for the development and management of a sustainable financial model for the Health ePeople Resource. Finally, the Administrative Core will furnish the administrative infrastructure to manage public relations, marketing, communications and dissemination of knowledge.