2019 Chronobiology GRC/GRS

项目摘要 我们请求部分支持第21届时间生物学戈登研究会议（GRC）和 伴随着第四次戈登研究研讨会（GRS），这将在举行 Rey Don Jaime Grand Hotel附近酒店 Castelldefels，巴塞罗那附近，西班牙，2019年6月23日至28日。 我们从国家卫生研究院得到的任何资金 用于部分支持主要是年轻研究人员，博士后研究员和 将参加GRC和相关GRS的研究生。诺贝尔生理学或医学奖 2017年，我们的同事Jeff Hall、Michael Rosbash和Mike Young因其在以下领域的开创性工作而获奖： 破译生物钟的分子基础确保了GRC/GRS将吸引广泛的 研究人员在许多不同的层次上使用不同的方法和模式生物。GRS将 专注于培训和指导，而GRC将展示高级和高级管理人员的最新未发表的工作， 领域的新星GRC的副主题是“模式生物中的时钟：昼夜节律网络， 生理学与健康'，并强调从许多不同的生物体研究的多样性 从分子、细胞、生理到行为和种群层面。这也包括 这些发现在诊所和工作场所的应用。因此，有一个广泛的主题 涵盖了时间生物学的大部分方面，使用各种生物和研究方法 包括在节目中。在高等生物体中，主生物钟位于大脑中， 现代生活方式对昼夜节律的破坏对人类行为、新陈代谢和 健康老龄化，所以会议很适合NINDS，NIA和NIDDK的范围。扬声器和 讨论领导者代表了该领域的资深人物和年轻的新星， 经与一个非正式委员会协商后选出，该委员会由联合国各机构的高级和初级人员组成， 领域男女发言人/会议主席人数几乎相等， 邀请来自美洲、欧洲和远东的国家发言，确保文化和性别平等。 多样性除导师计划外，研究组亦会邀请八位初级讲者，而研究组亦会进一步甄选 9份年轻科学家的摘要，作为主要会议上的简短演讲， 学员的学习经验。

Project Summary We request partial support for the 21st Chronobiology Gordon Research Conference (GRC) and the accompanying 4th Gordon Research Seminar (GRS), which will be held at the Rey Don Jaime Grand Hotel, Castelldefels, near Barcelona, Spain from June 23-28th 2019. Any funds that we receive from the NIH will be used to partially support the registration fees for predominantly younger researchers, postdoctoral fellows and graduate students who will attend the GRC and associated GRS. The Nobel Prize in Medicine or Physiology awarded in 2017 to our colleagues Jeff Hall, Michael Rosbash and Mike Young for their pioneering work in deciphering the molecular basis of the circadian clock ensures that both GRC/GRS will attract a wide-range of researchers working at many different levels with diverse methodologies and model organisms. The GRS will focus on training and mentorship, while the GRC will present the latest unpublished work from the senior and emerging stars of the field. The GRC subtheme is `Clocks in model organisms: Circadian Networks, Physiology and Health' and emphasizes the diverse range of organisms that are studied from many different perspectives, from the molecular, cellular, physiological to behavioral and population layers. This also includes the application of these findings to the clinic and workplace. Consequently there is a wide range of topics covering most aspect of chronobiology using a diverse range of organisms and research methodologies included within the program. In higher organisms, the master circadian clock is in the brain, and chronic circadian disruption by modern lifestyles has important implications for human behavior, metabolism and healthy ageing, so the conference fits well within the sphere of NINDS, NIA and NIDDK. The speakers and discussion leaders represent senior established figures and younger emerging stars of the field and have been selected by consultation with an informal committee consisting of both senior and more junior figures in the field. There is an almost equal number of male and female speakers/session chairs as well as a range of nationalities invited to speak, from the Americas, Europe and the Far East ensuring a cultural and gender diversity. Apart from the mentorship, the GRS will also have 8 junior speakers and the GRC will further select 9 abstracts from younger scientists for presentation as short talks at the main meeting, providing an important learning experience for the trainees.