UT StrokeNet

在过去的十年中，中风的预防、治疗、康复、 和康复。然而，对不同人群进行更多外部有效的有效性试验是至关重要的。 目前的中风试验受到低效的挑战，例如多机构审查 董事会、试验协议和试验网络，这可能会导致登记缓慢或不完整， 质量参差不齐，成本高。美国国立卫生研究院中风试验网络(StrokeNet)是由 解决这些问题的目的。使用中央IRB、主试验协议和 使用单一电子数据捕获系统(WebDCU)来减少 启动时间和提高数据质量。美国各地纳入中心的目标是增加 参与者数量和多样性。犹他健康大学(UUH)是一所非常成功的NIH StrokeNet区域协调中心。犹他州(UT)StrokeNet位于 西部山区，一个由5个州组成的地区，覆盖了美国陆地的10%，拥有1280万人口 居民的多样性日益增加。UT StrokeNet包括9个临床执行点(CP)，8个 成人和1名儿科，分别在犹他州、科罗拉多州和亚利桑那州。在下一个资助期，UT StrokeNet 将继续有效地实施并成功地开展多个成人和儿科 StrokeNet使用所有9个站点的综合实力进行试验。UT StrokeNet旨在提供访问 为所有西部山区中风患者提供高质量的创新试验，无论患者性别或性别 地点。UT StrokeNet将专注于通过提供文化服务来进一步增加少数族裔的招聘 对其研究团队进行能力培训，并最大限度地提高患者获得临床试验的机会 通过使用Telestroke网络生活在农村和边境地区。地方领导层 团队将继续在国家网络委员会任职，为StrokeNet做出贡献 行动。UT StrokeNet还将促进当地临床和医疗机构的多学科合作 翻译中风专家(重点关注中风康复)，以便提出 对NINDS和网络的创新试验。UT StrokeNet将促进教育和职业发展 培养博士后临床和翻译科学家 个性化培训计划，包括体验式学习、可选课程和 职业和研究指导。通过实现这些目标，UT StrokeNet将为 继续发展全国中风试验网络，推进中风研究， 最终，改善西部山区所有人的中风护理。

The last decade has seen significant advances in stroke prevention, treatment, rehabilitation, and recovery. Yet, more externally valid effectiveness trials with diverse populations are critical. Current stroke trials are challenged by inefficiencies, such as multiple institutional review boards, trial agreements, and trial networks, which can lead to slow or incomplete enrollment, variable quality, and high costs. The NIH Stroke Trials Network (StrokeNet) was founded with the purpose of addressing these issues. The use of a central IRB, Master Trial Agreement and use of a single electronic data capture system (webDCU) were implemented with to reduce start-up times and improve data quality. Inclusion of centers across the US aims to increase participant numbers and diversity. University of Utah Health (UUH) is a highly successful NIH StrokeNet Regional Coordinating Center (RCC). Utah (UT) StrokeNet is centered in the Mountain West, a 5-state region covering 10% of the U.S. landmass with 12.8 million inhabitants of increasing diversity. UT StrokeNet includes 9 Clinical Performing Sites (CPS), 8 adult and 1 pediatric, in Utah, Colorado, and Arizona. In the next funding period, UT StrokeNet will continue to efficiently implement and successfully conduct multiple adult and pediatric StrokeNet trials using the combined strength of all 9 sites. UT StrokeNet aims to provide access to high quality, innovative trials to all Mountain West stroke patients, regardless of patient sex or location. UT StrokeNet will focus on further increasing minority recruitment by providing cultural competency training to its study teams as well as maximizing access to clinical trials for patients living in rural and frontier areas through the use of the Telestroke Network. The local leadership team will continue to serve on national network committees to contribute to StrokeNet operations. UT StrokeNet will also facilitate multi-disciplinary collaborations of local clinical and translational stroke experts (with a strong focus on stroke rehabilitation) in order to propose innovative trials to NINDS and the Network. UT StrokeNet will foster the education and career development of post-doctoral clinical and translational scientists through a focused, individualized training program that includes experiential learning, optional coursework, and career and research mentoring. By achieving these goals, UT StrokeNet will contribute to the continued development of the national stroke trials network, advancement of stroke research, and, ultimately, an improvement of stroke care for all persons in the Mountain West.