Women and HIV: Translation of Research into Practice

 描述(由申请者提供)：为了在肯尼亚提供最佳的艾滋病毒治疗和预防妇女和青春期女孩中新的感染，有必要进行与当地相关的研究，以解决知识差距，并可以很容易地转化为国家指南、临床实践和政策。拟议的培训计划的主要目标是在肯尼亚医学研究所(KEMRI)建设以艾滋病毒、妇女和青少年为重点的实施科学的能力，同时建立与负责医疗实践和服务提供的其他组织的桥梁。KEMRI坚定地致力于开展研究，为肯尼亚的服务提供提供信息并改善国家健康结果，这构成了该计划的基础。华盛顿大学(UW)与KEMRI和其他肯尼亚机构，如国家艾滋病和性病控制计划(NASCOP)的长期合作加强了这一基础。该项目将由威斯康星大学医学、流行病学和全球健康教授、非洲两个大型艾滋病毒培训项目主任凯里·法夸尔博士和具有丰富研究经验的产科妇科医生伊丽莎白·布库西博士领导，她目前是KEMRI研究和培训部门的副主任。拟议计划的第一个目标是通过培训8名医学博士，在密歇根大学公共卫生学院提供硕士和博士课程，从而建立KEMRI和NASCOP的实施科学研究能力。在西雅图完成9个月的课程学习后，学员将返回肯尼亚9个月，在威斯康星大学、KEMRI和NASCOP核心学院团队的指导下，开展以妇女艾滋病毒治疗和预防为重点的实施科学研究项目。在此期间，他们还将在肯尼亚卫生部、疾病控制与预防中心-肯尼亚或其他从事妇女和青少年艾滋病毒护理和预防工作的政府或非政府组织完成外派工作。该计划的第二个目标将通过支持对研究生院在教学和研究方面出类拔萃的5名教员进行中期培训，进一步加强KEMRI的能力。在威斯康星州大学工作5个月后，教师将返回KEMRI讲授高级研究方法、实施科学和青少年和妇女健康方面的新课程，并完成与妇女和艾滋病毒有关的拨款申请或手稿。第三个目标将通过提供为期一周的实施科学、赠款编写和手稿准备讲习班，将培训范围扩大到更多的KEMRI和NASCOP工作人员；还将与KEMRI工作人员合作，为县医务主任举办为期一天的讲习班，以促进妇女受艾滋病毒疫情影响最严重的地区地方护理、治疗和预防领导人的参与。这一三级方法使用了威斯康星大学完善的培训方法，拟议的计划是在KEMRI及其合作伙伴组织NASCOP建立急需的实施科学研究能力，并改变肯尼亚妇女和青春期女孩艾滋病毒流行的面貌。

 DESCRIPTION (provided by applicant): To provide optimal HIV treatment and prevent new infections among women and adolescent girls in Kenya, it is necessary to conduct locally relevant research that addresses the know-do gap and can be readily translated into national guidelines, clinical practice and policy. The proposed training program's primary goal is to build capacity at the Kenya Medical Research Institute (KEMRI) in implementation science focused on HIV, women and adolescents while creating bridges to other organizations responsible for healthcare practice and service delivery. KEMRI's strong commitment to conducting research that informs service delivery and improves national health outcomes in Kenya forms the foundation for the program. This foundation is strengthened by the University of Washington's (UW) long-term collaboration with KEMRI and other Kenyan institutions, such as the National AIDS and STD Control Program (NASCOP). The program will be led by Dr. Carey Farquhar, UW Professor of Medicine, Epidemiology and Global Health, and Director of two large HIV training programs in Africa, and by Dr. Elizabeth Bukusi, an obstetrician-gynecologist with extensive research experience who is currently Deputy Director of Research and Training at KEMRI. The first aim of the proposed program will build implementation science research capacity at KEMRI and NASCOP by training 8 medical doctors in master's and doctoral programs offered by the UW School of Public Health. After 9 months of coursework in Seattle, trainees will return to Kenya for 9 months to conduct implementation science research projects focused on HIV treatment and prevention for women with guidance from a team of UW, KEMRI and NASCOP Core Faculty. During this period they will also complete an externship at the Kenya Ministry of Health, CDC-Kenya, or another governmental or non-governmental organization working in HIV care and prevention for women and adolescents. The program's second aim will further strengthen capacity at KEMRI by supporting medium-term training for 5 faculty who have excelled in teaching and research at the graduate school. After 5 months at UW, faculty will return to KEMRI equipped to teach new courses in advanced research methods, implementation science and adolescent and women's health and having completed a grant proposal or manuscript related to women and HIV. The third aim will extend the reach of training to a greater number of KEMRI and NASCOP staff by providing 1-week workshops on implementation science, grant writing, and manuscript preparation; 1-day workshops for county medical directors will also be offered in collaboration with KEMRI staff to promote engagement of local care, treatment and prevention leaders in areas where women are hardest hit by the HIV epidemic. This three-tiered approach uses UW's well-established approaches to training, the proposed program to build greatly needed implementation science research capacity at KEMRI and its partner organization NASCOP and change the face of the HIV epidemic for women and adolescent girls in Kenya.