Core H: AIDS Specimen Bank Core

艾滋病标本库（ASB）核心提供专业收集和冷冻保存的生物样本。 与详细临床信息相关联的标本，以实现多学科研究的桥接 以实验室为基础的基础科学与临床，行为和流行病学调查。的ASB 核心仍然是至关重要的CFAR转化研究工作，并寻求扩大范围， 它提供的服务，跟上CFAR发起的创新新实验方向的步伐 investigators.在本赠款周期，艾滋病样本库核心处理了127 000多份 样本，贡献了48份已发表的手稿，提供了21种不同类型的生物标本 处理和储存，并支助了由17名调查员领导的22项调查。核心回应 通过引入2种新的存储方法，积极满足CFAR调查人员不断变化的需求， 支持CFAR科学优先事项，包括艾滋病毒感染和健康的长期后果 差距。 ASB有一个杰出的声誉，从来没有失去一个标本，由于冷冻故障， 地震或停电。ASB最先进的库存系统还可以快速定位单个 在该银行的25个超低温和13个液氮冷冻机中，ASB继续寻求新的 通过改变处理和冷冻过程来提高冷冻保存过程中标本存活率的方法。 根据对UCSF-Gladstone CFAR调查人员需求的调查，ASB将扩大 它处理和储存的标本用于基础和转化研究。ASB还将提供其 为所有CFAR成员提供支持服务，包括位于国内或国际站点的成员。 UCSF艾滋病标本库（ASB）通过解决以下问题来支持CFAR的整体使命： 整个UCSF HIV研究社区的生物库需求。我们将通过以下方式实现这一目标： 1)持续提供高质量的生物标本处理、管理和储存服务， 各种各样的科学家; 2)为早期职业调查人员、研究人员和高级研究人员提供咨询和培训 受训人员; 3)投资于新方法，以提高标本的生存能力;以及 4)将Core转换为数据和样本管理的新技术解决方案。

The AIDS Specimen Bank (ASB) Core provides expertly collected and cryopreserved biological specimens linked to detailed clinical information to enable multidisciplinary research bridging laboratory-based basic science with clinical, behavioral, and epidemiological investigations. The ASB Core remains crucial to the CFAR translational research effort and has sought to expand the range of services it provides, keeping pace with the innovative new experimental directions initiated by CFAR investigators. In the current grant cycle, the AIDS Specimen Bank Core processed over 127,000 samples, contributed to 48 published manuscripts, provided 21 different types of biospecimen processing and storage, and supported 22 investigations led by 17 investigators. The Core responded to the changing needs of CFAR investigators by introducing 2 new storage methods and actively supported CFAR scientific priorities including long-term consequences of HIV infection and health disparities. ASB has an outstanding reputation for never having lost a specimen due to freezer malfunction, earthquakes, or power outages. ASB's state of the art inventory system can also quickly locate a single cryovial among the bank's 25 ultra-low and 13 liquid nitrogen freezers. ASB continues to seek new methods to improve specimen viability during cryostorage through changes in processing and freezing. Based on surveys of the needs of the UCSF-Gladstone CFAR investigators, ASB will expand the type of specimens it processes and stores for basic and translational research. ASB will also provide its services to support all CFAR members, including those based at either domestic or international sites. The UCSF AIDS Specimen Bank (ASB) supports the overall CFAR mission by addressing the biorepository needs of the entire UCSF HIV research community. We will achieve this goal by 1) Continuing to provide high-quality biospecimens processing, management and storage to a wide variety of scientists; 2) Offering consultation and training for early-career investigators, research staff, and advanced trainees; 3) Investing in new methods to improve specimen viability; and 4) Transitioning the Core to a new technology solution for data and specimen management.