Administrative Core

行政核心--项目摘要 密歇根化合物鉴定开发核心(MCIDC)将使用集成的计算和 在化合物鉴定领域推进与化合物鉴定有关的科学的实验方法 代谢组学。在共同基金代谢组学计划第二阶段的工作中，MCIDC将 与联盟成员和更大的科学界分享这些努力的成果。 MCIDC调查人员的工作将主要使用密歇根州现有的基础设施 代谢组学和肥胖中心(MMOC)，最近更名为密歇根代谢组学中心(MMC)， 谁监管共同基金支持的密歇根地区综合代谢资源核心 (U24)，儿童健康暴露分析资源(U2C)和物理分子传感器 活动(MoTrPAC(U24))赠款。管理核心MCIDC的总体目标是协调 MMC较大的代谢组学基础设施MCIDC内的活动，其他CIDC，NIH 共同基金代谢组学计划和更大的代谢组学社区。 为实现这一目标，行政核心将：提供协调和综合研究的基础设施 MCIDC计算核心和实验核心之间的关系，并促进它们之间的交互；管理人员 MCIDC及其在特定项目中的角色；确保所需的领导和资源可用 到计算和实验核心；充当与其他实体协调的接口 共同基金代谢组学联盟和更广泛的研究社区；监督MCIDC的预算 和支出；评估各核心在所需化合物鉴定任务方面的持续进展情况； 确定并消除在实现MCIDC科学目标方面稳步取得进展的任何障碍。

Administrative Core - Project Summary The Michigan Compound Identification Development Core (MCIDC) will use integrated computational and experimental approaches to advance sciences pertaining to compound identification in the field of metabolomics. Working within the second stage of the Common Fund Metabolomics Program, the MCIDC will share the results of these efforts with consortium members and with the larger scientific community. Work by MCIDC investigators will be performed largely using the existing infrastructure of the Michigan Metabolomics and Obesity Center (MMOC), recently renamed the Michigan Metabolomics Center (MMC), which oversees the Common Fund-supported Michigan Regional Comprehensive Metabolic Resource Core (U24), the Children's Health Exposure Analysis Resource (U2C) and the Molecular Transducers of Physical Activity (MoTrPAC (U24)) grant. The overall goal of the Administrative Core MCIDC is to coordinate the activities within the MCIDC, the larger metabolomics infrastructure of the MMC, the other CIDCs, the NIH Common Fund Metabolomics Program and the larger metabolomics community. To achieve this goal, the administrative core will: provide infrastructure to coordinate and integrate research between the MCIDC computational and experimental cores and facilitate their interaction; manage personnel in MCIDC and their roles within specific projects; ensure required leadership and required resources are available to the computational and experimental cores; act as an interface for coordination with other entities of the Common Funds Metabolomics Consortium and the broader research community; oversee MCIDC's budget and expenditures; and assess ongoing progress of the cores on required compound identification tasks, and identify and remove any barriers to steady progress towards completion of MCIDC's scientific objectives.