Precision Lifestyle Medicine and Translation Research (PREMIER)

项目总结/摘要 该提案寻求对精密生活方式医学和翻译研究的新T32的支持 在伊利诺伊大学芝加哥分校（UIC）接受高级培训。该计划的影响目标是建立一个 跨学科的，转化研究的博士后研究员谁渴望成为谁的培训基础设施 生活方式医学的独立研究者和团队科学家。具体来说，该计划解决了 预防和控制心血管和呼吸系统慢性疾病和合并症。具体 目的是：（1）招募和培养一批优秀的、多样化的研究员骨干;（2）提供一个学术“孵化器” 一个鼓舞人心的指导研究经验和个性化的专业发展;（3）维持一个 在所有学术级别的专用，熟练的导师管道。PREMIER有三个综合科学中心： 多发病预防和控制的行为科学作为中心，以患者为导向的研究- 行为和行为变化与人群健康的机制探索 Equity和Policy核心穿过中央核心。由内部和外部顾问提供支持 委员会，执行委员会，由2名PI和每个科学核心的2名共同领导人组成，将 提供知识领导和方案监督。这8名教员沿着还有其他21名来自6个 UIC的科学学院（医学，公共卫生，应用健康科学，药学，工程和 护理）是PREMIER导师，包括20名已建立的导师和9名新兴导师（他们将学习 通过观察、经验和培训掌握指导技能）。总的来说，他们带来了深入的研究 专业知识、丰富的专业经验和必要的资源。该计划将支持2 博士后职位在一年1，3年2-3，4年4-5，为2-3年的资金，与 根据申请的优点，MD和PhD之间的分配大致相等。每个人都会收到 由1名与研究员核心兴趣相关的主要、已建立的导师提供小组指导 以及来自其他核心的1-2个次级导师。其中一位导师必须具备以下方面的专业知识： 多发病预防和控制的行为科学。研究员将投入至少75%的努力， 指导研究，辅以会议，研讨会和课程（在适当的时候， 导致硕士学位，如临床转化科学硕士），基于个人 需求研究员将从当地，地区和全国范围内寻求研究的医学博士和博士中选出 在UIC培训，这是一个少数服务的高等教育机构资格。选择标准侧重于 过去的成就，特别是他们作为未来研究人员和教育工作者的潜力。每一位学员将 制定个人发展计划，并对进展情况进行持续监测和正式评估。 设计了一个多层次的方案评估计划，以确保持续供资的质量。

PROJECT SUMMARY/ABSTRACT This proposal seeks support for a new T32 in Precision Lifestyle Medicine and Translation Research (PREMIER) training at the University of Illinois at Chicago (UIC). The program impact goal is to build a transdisciplinary, translational research training infrastructure for postdoctoral fellows who aspire to be both independent investigators and team scientists in lifestyle medicine. Specifically, the program addresses the prevention and control of cardiovascular and respiratory chronic conditions and comorbidities. The specific aims are to: (1) Recruit and train a superb and diverse cadre of fellows; (2) Provide an academic “incubator” for an inspiring mentored research experience and individualized professional development; and (3) Sustain a pipeline of dedicated, skilled mentors at all academic ranks. PREMIER has 3 integrative scientific foci: Behavioral Sciences for Multimorbidity Prevention and Control as the central, patient-oriented research- focused core; and Mechanistic Explorations of Behavior and Behavior Change and the Population Health Equity and Policy cores traversing the central core. Supported by an Internal and External Advisory Committee, the Executive Committee, consisting of the 2 PIs and the 2 co-leaders of each scientific core, will provide intellectual leadership and programmatic oversight. These 8 faculty along with 21 others from 6 science colleges at UIC (Medicine, Public Health, Applied Health Sciences, Pharmacy, Engineering and Nursing) are PREMIER mentors, including 20 established mentors and 9 emerging mentors (who will learn mentorship skills through observation, experience, and training). Collectively, they bring deep research expertise, extensive professional experiences, and essential resources. The program will support 2 postdoctoral positions in year 1, 3 in years 2-3, and 4 in years 4-5, for 2-3 years of funding each, with approximately equal allocation between MDs and PhDs based on application merits. Every fellow will receive group mentorship from 1 primary, established mentor associated with the core of central interest to the fellow and 1-2 secondary mentors from the other cores. One of the mentors must have established expertise in Behavioral Sciences for Multimorbidity Prevention and Control. Fellows will devote at least 75% effort to mentored research, supplemented by conferences, seminars, and coursework (which, when appropriate, may lead to a master's degree, such as a Master of Science in Clinical Translational Science) based on individual needs. Fellows will be selected from a local, regional, and nationwide pool of MDs and PhDs seeking research training at UIC, which qualifies as a minority serving higher education institution. Selection criteria focus on past accomplishments and especially on their potential as future researchers and educators. Each trainee will develop an individual development plan, and progress is to be continuously monitored and formally evaluated. A multi-level program evaluation plan is designed to ensure quality for continued funding.