Improving Minority Health in Rheumatic Diseases

摘要 系统性红斑狼疮是一种重要的慢性疾病， 主要是有色人种的年轻女性。我们目前的P30 CCCR赠款“改善少数民族健康， “风湿病”由三个核心组成，即管理、方法和病人资源。 这些核心为旨在了解狼疮发病机制的研究提供了基础设施 和硬皮病作为实现对这些疾病的更好诊断和治疗的方法。在 在对P30的行政补充中，我们提出了两个具体项目，重点是 减少狼疮的种族差异将在MUSC和亚拉巴马大学进行， 伯明翰第一个项目是在年轻人中提供认识、教育和早期筛查， 非洲裔美国女性通过在历史上黑人学院的方案和努力， 南卡罗来纳州和亚拉巴马的大学。第二个项目是利用病人的倡导者， 高风险非洲裔美国女性狼疮患者基于错过的预约，药物治疗， 两个机构的依从性和ER访视。倡导者将与患者一起改善 这些参数相信，在狼疮中的这种导航将与在 艾滋病。我们还建议每年开展一个试点项目， 机构，为初级研究人员在健康差距和跨机构的指导计划 分享专业知识。CCCR计划不包括项目，而只包括核心。我们建议 利用这一补充机制，实施我们认为将对族裔群体产生直接影响的项目。 狼疮的差异

ABSTRACT Systemic Lupus Erythematosus is a significant chronic disease with morbidity and mortality in primarily young women of color. Our current P30 CCCR grant “Improving Minority Health in Rheumatic Diseases” is composed of three cores, administrative, methodology and patient resource. These cores provide the infrastructure for studies directed at understanding the pathogenesis of lupus and scleroderma as a method to achieve better diagnostics and treatments for these diseases. In this Administrative Supplement to the P30 we are proposing two specific projects focused on decreasing ethnic disparities in lupus to be performed at MUSC and the University of Alabama at Birmingham. The first project is to provide awareness, education and early screening in young African American females through programs and efforts at Historically Black Colleges and Universities in South Carolina and Alabama. The second project is to utilize a patient advocate for high risk African American female lupus patients based on missed appointments, medication non adherence and ER visits at both institutions. The advocate will work with the patients to improve these parameters believing that such navigation in lupus will be as successful as similar efforts in HIV. We also propose an enhancement effort consisting of a pilot project each year for both institutions, a mentoring program for junior investigators in health disparities and cross institutional sharing of expertise. The CCCR program does not include projects, but only cores. We propose to utilize this supplement mechanism to pursue projects we believe will have direct impact on ethnic disparities in lupus.