HIGH THROUGHPUT BIOMARKER-BASED BIODOSIMETRY

该计划的目标是开发一种高通量的生物剂量学测试，适用于放射性/核事故后的大规模伤亡情况。该设备，超高温生物剂量测定测试，将定量六个血液生物标志物在患者血浆样本中使用多重免疫测定和应用多参数算法来估计吸收的辐射剂量。在默沙东正在进行的生物剂量测定计划中，已开发并测试了辐射标记物，以开发分类测试

The goal of the program is to develop a high throughput biodosimetry test suitable for use in mass casualty situations following a radiological/nuclear incident. The device, the UHT Biodosimetry Test, will quantitate six blood biomarkers in patient plasma samples using multiplexed immunoassays and apply a multi-parameter algorithm to estimate absorbed radiation dose. The radiation markers have been developed and tested during MSD’s on-going biodosimetry program to develop a triage test