Maternal carriage of Prevotella during pregnancy influences offspring innate immune responses and asthma at age 7
Maternal carriage of Prevotella during pregnancy influences offspring innate immune responses and asthma at age 7
怀孕期间母亲携带普雷沃氏菌会影响后代 7 岁时的先天免疫反应和哮喘
批准号：
nhmrc : 1147980
负责人：
Dr Fiona Collier
金额：
$61.13万
依托单位：
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2018
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2018-01-01 至 2021-12-31
中文摘要
翻译
该项目将调查母亲怀孕期间肠道携带的细菌与婴儿患过敏性疾病和哮喘的风险之间的关系。我们将调查潜在的免疫途径，并在小鼠身上进行实验，以确定为母亲接种一种名为普雷沃特拉菌的特定类型的细菌是否可以用于预防后代的食物过敏和哮喘。
英文摘要
This project will investigate the relationship between the bacteria a mother carries in her gut during pregnancy and her baby’s risk of developing allergic disease and asthma. We will investigate underlying immune pathways and conduct experiments in mice to determine whether inoculating mothers with a specific type of bacteria known as Prevotella could be used to prevent food allergies and asthma in the offspring.
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