Developmental Core

核心B：发育 摘要 发展核心（Core B）是宾夕法尼亚大学CFAR活动的基石，催化了新的研究方向 在艾滋病毒/艾滋病优先领域，通过指导计划加强研究渠道，确保下一个 培养艾滋病毒调查人员和研究领导人，吸引新的艾滋病调查人员， Penn CFAR战略科学优先事项。发展核心对于建立新的 艾滋病毒/艾滋病独立调查员和新的研究领域提供指导、建立伙伴关系和资助活动。 自1999年设立核心计划以来，该计划已资助了101项试验赠款，总额为396万美元，收益为8240万美元 在随后的NIH基金中，投资回报率（ROI）为21：1;在过去的10年中，它已经资助了62 250万美元的试点赠款，导致NIH赠款总额为6240万美元（25：1的投资回报率）。核心B由巴勃罗博士领导 Tebas（主任）和Luis Montaner（联合主任）。发展核心目标是： 1.为了培训和指导下一代艾滋病研究人员和艾滋病研究领导者，鼓励 让其他领域的资深研究人员参与艾滋病毒/艾滋病研究， 调查人员在该领域通过：（1）教育，指导，和合作计划，以提供咨询，支持， 和领导新出现的和新的艾滋病调查;（2）广泛参与CFAR社区， 通过与其他核心和CFAR教师的合作和协调进行指导;（3）实施一系列 研讨会，工作组和审查小组，汇集了来自相互关联领域的调查人员， 以便向新的研究人员提供反馈，并培养跨学科的互动。 2.提供新的资助机制，支持创新的研究计划，并作为一个 研究培训的工具，通过：（1）发展试点赠款计划，资金高达6 发展项目，每年针对新的和新的艾滋病毒研究人员，和/或新的跨学科 （2）一个伙伴关系试点赠款计划，利用资源，并创造协同作用，与其他团体， CFAR校园;（3）一个新的小额赠款赠款计划，为初级研究人员提供灵活，快速的资金 获得有针对性的数据，以便重新提交赠款或支持在重要的科学会议上发表演讲。 3.促进CFAR和NIH HIV/AIDS研究优先领域的研究， 跨学科合作研究，并通过以下方式与校园和社区合作伙伴互动：（1）创建一个 环境，汇集了来自基础，临床和行为科学的研究人员;（2）参与 校园研究人员和费城社区合作伙伴在推广到学校，部门和部门 在校园里，并加强与费城公共卫生部和社区的合作- （3）指导导师活动和资助计划，以支持新的艾滋病服务组织。 研究人员和发展艾滋病毒/艾滋病优先研究领域的职业生涯;（4）将资助计划用于 CFAR的优先领域，包括其科学工作组。

Core B: Developmental ABSTRACT The Developmental Core (Core B) is the keystone of Penn CFAR activities catalyzing new research directions in HIV/AIDS priority areas, enhancing the research pipeline through mentoring programs that ensure the next generation of HIV investigators and research leaders and attracting new-to-AIDS investigators, and advancing Penn CFAR strategic scientific priorities. The Developmental Core has been critical for the establishment of new independent HIV/AIDS investigators and new research areas by its mentoring, partnering and funding activities. Since creation of the Core in 1999, it has funded 101 pilot grants with a total of $3.96M, yielding $82.4M in subsequent NIH funds for a 21:1 return on investment (ROI); over the past 10 years it has funding 62 pilot grants with $2.5M, resulting in NIH grants totaling $62.4M (25:1 ROI). Core B is led by Drs. Pablo Tebas (Director) and Luis Montaner (Co-Director). The Developmental Core aims are: 1. To train and mentor the next generation of HIV investigators and leaders in AIDS research, encourage entry of established investigators from other areas into HIV/AIDS research, and enhance the diversity of investigators in the field through: (1) Education, mentoring, and partnering programs to provide advice, support and leadership for emerging and new-to-AIDS investigators; (2) Broadly engaging the CFAR community in mentoring through collaboration and coordination with other Cores and CFAR faculty; (3) Implementing a series of Workshops, Working Groups, and Review Panels that bring together investigators from interrelated areas in order to give feedback to new investigators and to nurture interdisciplinary interactions. 2. To provide novel funding mechanisms that support innovative research initiatives, and serve as a vehicle for research training through: (1) The Developmental Pilot Grant program that funds up to 6 developmental projects each year, targeting new and new-to-HIV investigators, and/or new interdisciplinary teams; (2) A Partnership Pilot Grant program that leverage resources and create synergy with other groups on the CFAR campus; (3) A novel Microgrant Grant Program to provide nimble, rapid funding for junior investigators to obtain targeted data for resubmission of a grant or support presentations at important scientific meetings. 3. To catalyze research in CFAR and NIH HIV/AIDS research priority areas and the development of interdisciplinary collaborative research, and engage campus and community partners by: (1) Creating an environment that brings together investigators from the basic, clinical and behavioral sciences; (2) Engaging campus researchers and Philadelphia community partners in outreach to Schools, Departments and Divisions on campus, and enhancing collaborations with the Philadelphia Department of Public Health and community- based AIDS service organizations; (3) Directing mentorship activities and funding initiatives to support new investigators and to develop careers in HIV/AIDS priority research areas; (4) Directing funding initiatives to priority areas for the CFAR including its Scientific Working Groups.