Rural Health Research and Delivery Core

项目总结 新英格兰北部的农村地区在健康状况、医疗保健机会和临床治疗方面存在差距 导致发病率和死亡率增加的后果。使这个问题变得更加复杂的是，农村提供者和 人们在临床试验和卫生服务研究活动中的代表性严重不足。改进 人口健康取决于从基础科学到临床研究的成功转化，以及 随后通过实施科学和公共政策得到更广泛的采用。此翻译 SPECTRUM需要与临床实践紧密联系，不仅作为创新想法的试验场，而且 也可以作为一个环境，在这个环境中，现实世界的问题可以被识别、表征并提出为 研究的目标。农村卫生研究和提供(RHRD)核心的广泛目标是开发和 支持新英格兰北部学术机构和农村实践之间的伙伴关系，以 成功开展临床和转化性研究。为了实现这一目标，我们将开展一系列 旨在：1)在学术中心和农村实践之间建立双向伙伴关系 为了激发研究想法，促进临床和转化性研究，并测试策略以改进 卫生；2)发展基础设施，支持农村实践研究；3)提高研究能力 通过改进数据访问、数据标准化，并与临床研究设计合作， 流行病学和生物统计核心(CRDEB)提供培训和访问最先进的观察 和临床研究方法。这些目标将得到参与农村实践的战略的支持。 研究企业以及与学术研究合作伙伴之间的关系 合作可拓模型方法。这包括创造创新的新的研究专业人员 缅因州和佛蒙特州的职位，以实践为基础的研究催化剂，谁将促进沟通和 建立学院和社区之间的关系，并将支持发展和实施 研究项目。我们还将为学术界的研究人员提供正式和非正式的机会 中心和公共/社区卫生专业人员与乡村临床医生见面并工作，并收集 来自乡村临床医生及其执业组织的定性数据，以了解潜在的好处和 参与临床和转化性研究的障碍。最后，我们将扩大北新区 英国医疗服务提供者参与卫生观察数据、科学和信息学平台 由临床医生、研究人员和数据科学家组成的创新社区致力于提高数据可比性 以及稳健的研究方法，用于观察性和其他临床研究。RHRD的活动 核心将涉及与该提案中的所有其他核心的合作。特别是，将有活动在 与CRDEB、试点项目和专业发展核心建立伙伴关系。

PROJECT SUMMARY Rural areas of Northern New England suffer from disparities in health status, health care access and clinical outcomes that lead to increased morbidity and mortality. Compounding this problem, rural providers and populations are seriously under-represented in clinical trials and health services research activities. Improving population health depends on successful translation of findings from basic science to clinical research, and subsequently to broader adoption through implementation science and public policy. This translational spectrum requires strong connections to clinical practice, not only as a testing ground for innovative ideas, but also as an environment in which real-world problems can be identified, characterized and brought forward as targets for research. The broad goal of the Rural Health Research and Delivery (RHRD) Core is to develop and support a partnership between academic institutions and rural practices in Northern New England to successfully carry out clinical and translational research. To achieve this goal we will engage in a series of activities designed to: 1) create a bi-directional partnership between academic centers and rural practices in order to stimulate research ideas, facilitate clinical and translational research, and test strategies to improve health; 2) develop the infrastructure to support research in rural practices; and 3) enhance research capacity through improved data access, data standardization, and, in collaboration with the Clinical Research Design, Epidemiology, and Biostatistics Core (CRDEB), provide training and access to state-of-the art observational and clinical research methodologies. These aims will be supported by strategies to engage rural practices in the research enterprise and in relationships with academic research partners in a team science and cooperative extension model approach. This includes the creation of innovative new research professional positions in Maine and Vermont, Practice-based Research Catalysts, who will facilitate communication and relationship building between academy and community, and will support the development and implementation of research projects. We will also develop formal and informal opportunities for researchers from academic centers and public/community health professionals to meet and work with rural clinicians, and collect qualitative data from rural clinicians and their practice organizations to understand the potential benefits and perceived barriers of participating in clinical and translational research. Finally, we will expand Northern New England providers' participation in the Observational Health Data, Science and Informatics platform, an innovative community of clinicians, researchers and data scientists committed to improving data comparability and robust research methodologies for observational and other clinical research. The activities of the RHRD core will involve collaboration with all of the other cores in this proposal. In particular, there will be activities in partnership with the CRDEB, Pilot Projects, and Professional Development Cores.