Biolibrary and Pathology

生物与病理共享资源 导演：Devon Kelly，M.S.和George Thomas，M.D. 摘要/项目摘要 奈特癌症研究所(Knight)赞助的生物图书馆和病理学共享资源汇聚在一起 将组织收集、处理、临床注释和组织病理学服务整合到一个核心中。该单位 为成员提供：1)注释良好的人体组织、血液和唾液的储存库，2)数据库 带注释的临床变量，包括患者人口统计、治疗和临床结果；研究 和临床试验参与；基因图谱、研究分析和标本成像；3)定制数据 以客户指定的病例报告的形式，4)人类和动物组织研究的病理学服务， 包括低温恒温器切片、石蜡包埋、切片、组织化学染色、 免疫组织化学、免疫荧光和荧光原位杂交，5)支持生产 来自冷冻和固定标本的高质量RNA和DNA样本，以及6)获奖前咨询 准备赠款和其他资金申请。生物文库和病理学共享资源是 通过美国病理学家学会(CAP)认证，并正在改进临床实验室 修订(CLIA)认证。它的工作人员都有几十年的综合经验 处理小动物和人类的样本，以确保组织得到适当的准备，以满足 研究界的各种需求，既用于即时分析，也用于长期存储和 使用。

BIOLIBRARY & PATHOLOGY SHARED RESOURCE Directors: Devon Kelly, M.S. and George Thomas, M.D ABSTRACT/PROJECT SUMMARY The Knight Cancer Institute (Knight) sponsored BioLibrary & Pathology Shared Resource brings together tissue collection, processing, clinical annotation, and histopathology services into a single core. The unit provides members with: 1) a repository of well-annotated human tissue, blood and saliva, 2) a database of annotated clinical variables including patient demographics, treatments and clinical outcomes; research and clinical trial participation; genetic profiles, research analyses and specimen imaging, 3) tailored data in the form of client-specified case reports, 4) pathology services for studies on human and animal tissues, including cryostat sectioning, paraffin-embedding, microtome-sectioning, histochemical staining, immunohistochemistry, immunofluorescence and fluorescent in situ hybridization, 5) support in producing high quality RNA and DNA samples from both frozen and fixed specimens, and 6) pre-award consulting for preparation of grant and other funding applications. The BioLibrary & Pathology Shared Resource is accredited through the College of American Pathologists (CAP) and is Clinical Laboratory Improvement Amendments (CLIA) certified. It is staffed with members who have decades of combined experience in handling samples from small animals and human to ensure that tissues are properly prepared to meet the various needs of the research community, both for immediate analyses as well as long-term storage and use.