Developmental Research Program

摘要：发展研究计划。爱荷华州大学/马约诊所的目标是 淋巴瘤孢子（孢子）发展研究计划（DRP）是支持创新，科学 健全的项目，调查有关的问题转化淋巴瘤的研究。这个程序 在过去5年中，在15个发展研究项目的支持下，继续取得成功。 其中5个项目获得了第二年的资助。DRP的四个奖项直接促成了 开发本次更新中提出的全部项目。一个额外的裁决导致了一个跨孢子试验， 更新。在下一个资助期内，DRP将提供为期一年的最高50，000美元（25，000美元来自SPORE 每年向四个项目中的每一个项目提供25，000美元， 基于进展和承诺的第二年支持。高风险/高回报的创新概念是 鼓励。预计DRP的支持将继续导致新假设的产生 将在SPORE赞助的研究中进行测试，或通过同行评审的外部赠款支持。很长的- SPORE计划的长期目标是将发展项目产生的结果转化为 降低淋巴瘤的发病率和死亡率。 DRP的具体目标是 1.鼓励淋巴瘤的创新实验室和预防相关临床研究 2.促进基础科学、临床和人口学科之间的广泛合作， 淋巴瘤转化研究 3.鼓励研究人员评估将其研究成果应用于翻译的潜力 淋巴瘤研究 4.生成新的假设，在临床试验中在SPORE内部和外部进行测试， 导致淋巴瘤患者护理的显著改善

ABSTRACT: Developmental Research Program (DRP). The goal of the University of Iowa / Mayo Clinic Lymphoma SPORE (SPORE) Developmental Research Program (DRP) is to support innovative, scientifically sound projects that investigate questions pertinent to translational lymphoma research. This program continued to be successful with support over the past 5 years going to 15 developmental research projects. Five of these projects received a second year of funding. Four of the DRP awards directly contributed to the development of the full Projects proposed in this renewal. An additional award led to an inter-SPORE trial in the renewal. In the next funding period, the DRP will provide up to $50,000 for one year ($25,000 from SPORE funds and $25,000 from institutional resources) to each of four projects each year with the possibility of a second year of support based on progress and promise. High risk/high payoff innovative concepts are encouraged. It is anticipated that support of DRP will continue to result in the generation of new hypotheses that will be tested in SPORE-sponsored research or through peer reviewed external grant support. The long- term goal of the SPORE program is to translate the findings generated by developmental projects into a reduction in the incidence and mortality rates of lymphoma. The Specific Aims of the DRP are to 1. Encourage innovative laboratory and translationally relevant clinical studies in lymphoma 2. Foster extensive collaboration between basic science, clinical and population-based disciplines in translational research in lymphoma 3. Encourage investigators to evaluate the potential of applying their research findings to translational research in lymphoma 4. Generate new hypotheses to be tested both inside and outside the SPORE in clinical trials that may lead to significant improvements in care of patients with lymphoma