MIGRATORY CHARACTERISTICS OF SKIN-DERIVED NEURAL PRECURSORS AS A NOVEL REGENERATIVE THERAPY FOR ALZHEIMER’S DISEASE
MIGRATORY CHARACTERISTICS OF SKIN-DERIVED NEURAL PRECURSORS AS A NOVEL REGENERATIVE THERAPY FOR ALZHEIMER’S DISEASE
批准号:
nhmrc : 1150414
负责人:
金额:
$3.13万
依托单位国家:
澳大利亚
项目类别:
Postgraduate Scholarships
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2019-12-31
中文摘要
阿尔茨海默氏症的记忆力下降与神经元的大量丧失以及这些细胞之间的联系有关。干细胞疗法有可能通过给大脑补充健康的功能性神经元来对抗这种神经元损失。这项研究旨在开发一种新型的神经干细胞,称为皮肤来源的神经前体,可以从患者自己的皮肤中分离出来。这项工作的结果将为人体临床试验的进展提供必要的数据。
英文摘要
Memory decline in Alzheimer's disease is linked to a massive loss of neurons and the connections between these cells. Stem cell therapy has the potential to combat this neuronal loss by replenishing the brain with healthy functional neurons. This study aims to develop a new type of neural stem-like cell, termed skin-derived neural precursors, which can be isolated from a patient’s own skin. The outcomes from this work will provide the necessary data for progress into human clinical trial.
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