Developmental Research Project Program

发展性研究项目计划摘要 发展研究项目方案(DRPP)将支持扩大调查人员队伍 在INBRE IV下的HiSREP网络，进而大幅扩大容量，从而为 夏威夷的生物医学研究。在INBRE III取得成功的基础上，DRPP将重点放在 在三个主要本科院校(PUI)有前途的初级调查人员(JIS)，INBRE IV中的DRPP将 此外，还为各级调查人员提供多种有竞争力的资助机制，a 更丰富的专业发展计划，以及更广泛、更有组织的核心设施、仪器和 生物信息学/生物统计学支持。除了在我们的PUIS上识别新的JIS之外，新的竞争对手 授予机制将是：试点项目、新倡议、合作资助和博士后教学 奖学金。对于所有的赠款，将鼓励合作；但是，对于协作赠款，优先 将提供由一名PUI调查员和一名R1领导机构在职业生涯中期或高级阶段提出的联合建议 作为综合研究团队的一部分，他是一名调查员。所有研究与这两个主题的联系，自然 将特别强调产品和分子医学，特别是通过提供独特的资源， 例如生物信息库和项目专业知识，例如密歇根大学癌症中心天然产品和 实验治疗(NPET)计划。对于获奖者，期望和结果将以 科学和职业指导计划，由PUIS和CCS的教师-学者模式平衡， 教学需求很大的地方。这将与透明的调查员、项目和 行政评估，导致建设性的交流和应对行动计划。最后，一个强有力的 牵头机构的支助作用是提供资源准入(赠款管理、核心工具 设施、组织和动物工作、生物信息学、生物统计学)。 DRPP将通过三个具体目标实现其目标：(1)提供催化资金以支持 在HiSREP网络的调查人员范围内新出现的研究；(2)提供多方面的 为新兴调查人员提供指导和专业发展计划；以及(3)支持和扩大 核心设施。

DEVELOPMENTAL RESEARCH PROJECT PROGRAM SUMMARY The Developmental Research Project Program (DRPP) will support an expanded cadre of investigators in the HiSREP network under INBRE IV, substantially expanding, in turn, the capacity and hence opportunity for biomedical research in Hawaii. Building on the success in INBRE III where the DRPP focused support on promising junior investigators (JIs) at three primarily undergraduate institutions (PUIs), DRPP in INBRE IV will additionally offer multiple competitive funding mechanisms with opportunity for investigators at all levels, a richer program in professional development, and wider, organized access to core facilities, instrumentation and bioinformatics / biostatistics support. In addition to identification of new JIs at our PUIs, the new competitive granting mechanisms will be: Pilot Projects, New Initiatives, Collaborative Grants and Teaching-Postdoctoral Fellowships. For all of the grants, collaborations will be encouraged; however, for Collaborative Grants, priority will be given for joint proposals from a PUI investigator and a R1 Lead Institution mid-career or senior investigator as part of an integrated research team. Connection of all research to the two themes, Natural Products and Molecular Medicine, will be emphasized, particularly through availability of unique resources, such as biorepositories, and programmatic expertise, such as the UH Cancer Center Natural Products & Experimental Therapeutics (NPET) program. For awardees, expectations and outcomes will be guided by scientific and career mentoring plans, balanced by the teacher-scholar model for faculty at PUIs and CCs, where teaching demands are significant. This will be coupled to transparent investigator, project and administration assessments, leading to constructive exchange and responsive action plans. Lastly, a strongly supportive role for the lead institution is providing resource access (grant management, core instrument facilities, tissue and animal work, bioinformatics, biostatistics). DRPP will accomplish its objectives through three specific aims: (1) Provide catalytic funding to support emerging research across the spectrum of investigators in the HiSREP network; (2) Provide multifaceted mentoring and professional development programs to emerging investigators; and (3) Support and expand core facilities.