CWRU- Cardiovascular Research Training Program

项目总结/摘要 该心血管研究培训计划（CRTP）的目标是提供基础方面的优秀培训， 心血管研究，有前途的博士前学生和高素质的MD或博士博士后研究员。 该计划包括来自6个博士课程和4个临床部门的29名高级培训师和8名初级培训师， 凯斯西储大学被招募的教师以卓越的研究而闻名， 资金和强大的研究空间。心血管研究所（CVRI）作为整合 为所有培训师提供平台。培训的重点是将分子和细胞的基本方法 生物学、生理学、生物物理学、生物医学工程和成像到机械问题和难题 与健康和疾病中的心血管系统有关，特别强调（a）心血管 代谢和炎症，（B）心脏功能、衰竭和心律失常，（c）血管病理生理学，和 (d)心血管组织工程与成像。大部分学生的招聘是通过医疗 科学家和生物医学科学培训计划，包括对招聘 妇女和代表性不足的少数民族。博士前培训是在生物医学博士课程完成 工程学、流行病学和生物统计学、分子医学、药理学、病理学和生理学& 生物物理学这些部门提供的基本课程和研究技能指导培训 CRTP的具体组成部分补充和增强了这些方案。其中包括完成所需的 心血管生理学研究生课程，一个令人兴奋的心血管沉浸式体验 医疗保健，参加每周一次的系列研讨会，每月一次的期刊俱乐部和每年一次的CVRI研究 退一个CRTP教师委员会，包括高级培训师和初级培训师，他们正在开发 心血管研究前沿领域的独立项目，指导每一位学员。博士后 学员，包括来自哈灵顿医师科学家途径的医生，通过他们的任命， 招募到CRTP培训师实验室，并将参加心血管保健沉浸，CVRI 研讨会/务虚会/期刊俱乐部，以及指导过程。本申请共寻求8个职位（4 博士生和4名博士后）。

Project Summary/Abstract The goal of this Cardiovascular Research Training Program (CRTP) is to provide outstanding training in basic cardiovascular research to promising predoctoral students and highly qualified MD or PhD postdoctoral fellows. The program includes 29 senior trainers and 8 junior trainers from 6 PhD programs and 4 clinical divisions at Case Western Reserve University. The recruited faculty are known for excellence in research, ample NIH funding, and robust research space. The Cardiovascular Research Institute (CVRI) serves as the integrating platform for all trainers on this grant. Training focuses on relating the basic approaches of molecular and cellular biology, physiology, biophysics, biomedical engineering, and imaging to mechanistic questions and problems pertinent to the cardiovascular system in health and disease, with particular emphasis on (a) Cardiovascular metabolism and inflammation, (b) Cardiac function, failure, and arrhythmia, (c) Vascular pathophysiology, and (d) Cardiovascular tissue engineering and imaging. The majority of student recruitment is through the Medical Scientist and Biomedical Sciences Training Programs, and includes a strong commitment to the recruitment of women and under-represented minorities. Predoctoral training is accomplished in PhD programs in Biomedical Engineering, Epidemiology & Biostatistics, Molecular Medicine, Pharmacology, Pathology, and Physiology & Biophysics. The basic coursework and guided training in research skills provided by these departmental programs is supplemented and enhanced by CRTP-specific components. These include completion of a required graduate course in Cardiovascular Physiology, an exciting Immersion Experience in Cardiovascular Healthcare, participation in a weekly seminar series, a monthly journal club, and an annual CVRI research retreat. A CRTP faculty committee that includes senior trainers and junior trainers, who are developing independent programs in cutting-edge areas of cardiovascular research, mentor each trainee. Postdoctoral trainees, including physicians from the Harrington Physician Scientist Pathway, are appointed via their recruitment to CRTP trainer labs and will also participate in the Cardiovascular Healthcare Immersion, CVRI seminars/retreats/journal club, and the mentoring process. In total, this application seeks 8 positions (4 predoctoral and 4 postdoctoral) per year.