Optimizing SARS-CoV-2 Testing and Promotores Interventions to Serve Latinx Communities

项目总结 全球SARS-CoV-2大流行是美国和世界近年来面临的最严重的健康危机 世纪。尽管这种高度传染性的病毒已经感染了数千万美国人，但大流行 远未结束，疾病负担继续不成比例地出生于历史上得不到足够的服务 拉丁裔社区等群体。在全国范围内，拉丁裔新冠肺炎携带者在四点住院 是白人的三倍，发病率和死亡率要高得多。这种差异在以下方面尤为显著 俄勒冈州，该州13%的人口为拉丁裔，约占新冠肺炎病例的24%。 然而，拉丁裔的疫苗接种率仍然低于该州的平均水平。因此，迫切需要达到 俄勒冈州的拉丁裔社区提供公共卫生和预防信息，强调继续 新冠肺炎测试和这解决了疫苗的犹豫问题。这个项目将建立在我们成功的RADx-UP基础上 第一阶段：通过实施第二阶段，因地制宜地开展社区外展和测试方案 目标是增加测试的覆盖率和接受度，减少拉美裔人群中疫苗接种的迟疑 俄勒冈州。该项目将保持和扩大一支世界级的预防科学家、公共卫生 专家、Latinx研究人员、社区合作伙伴和生物学家一直在共同努力进行 自2020年3月开始进行SARS-CoV-2诊断检测。该团队建立了CLIA认证的实验室，并 完善的分子检测方案，采购了数百万美元的诊断检测设备和用品， 并与全州的县公共卫生办公室和医院合作进行检测。该队 利用基于社区的参与性研究，参与了全面的社区伙伴关系 方法在第一阶段提供文化量身定做的干预措施，在增加 在拉丁裔个体中进行测试。基于我们在第一阶段RADX-UP的前6个月中学到的经验教训 测试，我们将重新关注我们现有的测试计划，通过与州政府和 为俄勒冈州的拉丁裔社区提供其他服务的社区组织。在持续的支持下 来自Latinx社区和科学咨询委员会的该项目将重新聚焦于支持100 每个月在俄勒冈州的个人，特别专注于在场馆定位测试事件 为拉丁裔个人提供服务(例如，墨西哥领事馆在全州的流动活动)。之前的 已启动的健康干预措施(Promotores De Salud)也将重新确定重点，以促进继续 将对这些重要健康行为的检测和疫苗接种情况以及障碍进行评估。随着时间的推移, 该项目将继续帮助社区将最优的本地测试框架制度化 可持续发展。由此产生的测试以及结构和系统将为未来的扩展做好准备 脆弱社区和/或用于其他公共卫生目的。这一项目预计将导致一项重大的 缩小服务不足人群中的新冠肺炎健康差距。

PROJECT SUMMARY The global SARS-CoV-2 pandemic is the worst health crisis the United States and world have faced in a century. Although this highly contagious virus has infected tens of millions of Americans already, the pandemic is far from over, and the disease burdens continue to be disproportionately born by historically underserved populations such as Latinx communities. Nationally, Latinx people with COVID-19 are hospitalized at four times the rate of Whites and have much higher rates of morbidity and mortality. This disparity is notable in Oregon, where the 13% of our population that is Latinx represents approximately 24% of COVID-19 cases. Yet, vaccination rates for Latinx remain below the state average. Thus, an urgent need exists to reach Oregon’s Latinx community with public health and prevention messages that emphasize the value of continued COVID-19 testing and that address vaccine hesitancy. This project will build upon our successful RADx-UP Phase I culturally-tailored community outreach and testing program through the implementation of Phase II goals of increasing the reach and uptake of testing and decreasing vaccine hesitancy in Latinx individuals in Oregon. The project will maintain and expand a world-class team of prevention scientists, public health experts, Latinx researchers, community partners, and biologists who have been working together to conduct SARS-CoV-2 diagnostic testing since March 2020. This team established a CLIA-certified laboratory and honed molecular testing protocols, procured millions of dollars of diagnostic testing equipment and supplies, and partnered with county public health offices and hospitals throughout the state to conduct testing. The team has been engaged in comprehensive community partnerships using community-based participatory research methods in Phase I to deliver a culturally-tailored intervention that shows preliminary efficacy in increasing testing among Latinx individuals. Building on the lessons learned in the first 6 months of our Phase I RADX-UP testing, we will refocus our existing testing program to broaden our reach by partnering with state and community organizations offering other services to Latinx communities across Oregon. With continued support from the Latinx Community and Scientific Advisory Board, the project will refocus to support the testing of 100 individuals each month across the state of Oregon, focusing specifically on locating testing events at venues that serve Latinx individuals (e.g., mobile Mexican Consulate events across the state). The previously launched health intervention (Promotores de Salud) will also be refocused to promote the benefits of continued testing and vaccination uptake, and barriers to these important health behaviors will be evaluated. Over time, this project will continue to help communities institutionalize optimal local testing frameworks that are sustainable. The resulting testing and structures and systems will be poised for future scale-up to other vulnerable communities and/or for other public health purposes. This project is expected to lead to a major reduction in COVID-19 health disparities in underserved populations.