Health Disparities in Alzheimer's Disease: Intergenerational and Sociocultural Contributors to Dementia Literacy in Immigrant Latinx Families

项目摘要 西班牙裔移民老年人患阿尔茨海默病和相关痴呆症的风险更大 （ADRD），并承担不成比例的相关并发症的负担。拟议 这项研究的最终目的是通过绘制痴呆症识字的结构来减轻这种负担（即， 了解疾病的原因、治疗方法和对疾病的态度）， 文化特异性疾病的看法，可用于未来的干预研究。 目前，标准的早期ADRD疾病检测对拉丁移民缺乏足够的有效性。 由于缺乏以证据为基础的科学，将文化和社会差异纳入 帐户.通过横断面设计，旨在为未来的假设提供试点数据- 在其他移民群体的驱动干预研究，拟议的研究将显着扩大 移民中的痴呆症知识基础。一种新颖的、以家庭为基础的招聘 一种以祖父母是移民的大学生为中心的方法，将被应用于招收200名 拉丁裔成年人用于收集问卷和基于调查的痴呆评估 文化适应、移民和其他社会文化因素 英语/西班牙语专业的经验和学位。拟议研究 环境非常适合这个建议的成功。皇后学院是西班牙裔 服务机构和周围社区是家庭最大的集中， 纽约州的移民。首席研究员有文化认知史 在一些疾病状态，包括痴呆症的调查，并将利用拟议的 在皇后学院学习以促进她的独立。合作研究员莫妮卡·里维拉·明特博士 是拉丁健康差异方面的专家，资助完成对艾滋病毒+痴呆风险的研究 拉丁裔长者，并与申请人成功合作的历史。 .

Project Summary Hispanic immigrant elders are at greater risk for Alzheimer’s disease and related dementias (ADRD) and carry a disproportionately heavier burden of related complications. The proposed study ultimately aims to reduce this burden by mapping the architecture of dementia literacy (i.e., knowledge about the causes, treatments and attitudes towards the disease) and identifying culturally-specific disease perceptions that can be utilized for future interventional studies. Currently, standard early ADRD disease detection lacks adequate validity for Latinx immigrant elders due to the absence of evidence-based science that take culture and social disparities into account. Through a cross-sectional design purposed to supply pilot data for future hypothesis- driven intervention studies in other immigrant groups, the proposed study will significantly expand the current dementia literacy knowledge base in immigrants. A novel, family-based recruitment method, centered on college students with immigrant grandparents, will be applied to enroll 200 Latinx adults for the collection of questionnaires and survey-based assessments of dementia literacy and a comprehensive panel of sociocultural factors such as acculturation, immigration experience and degree of English/Spanish language proficiencies. The proposed research environment is ideally suited for the success of this proposal. Queens College is a Hispanic Serving Institution and the surrounding community is home to the largest concentration of immigrants in New York State. The Principle Investigator has a history of cultural cognitive investigations in a number of diseased states, including dementia, and will utilize the proposed study to propel her independence at Queens College. Co-investigator, Dr. Monica Rivera-Mindt, is an expert in Latinx health disparities, funded to complete research on dementia risk in HIV+ Latinx elders and has a history of successful collaboration with the applicant. .