Core 1: Administrative Core

行政核心1 摘要 该计划项目的总体目标是设计和开发泛β冠状病毒（panbetaCoV）疫苗， 2b和2c组的betaCoV将在下一次冠状病毒爆发时可用。本项目 将有四个项目，一个行政核心和两个支持共享资源核心。为了支持成功 行政核心将协调和监督科学和行政活动， 确保所有项目和核心协同并保持符合联邦和州法规的所有方面。 财务管理、行政管理以及跨项目和核心资源共享将 成为这个核心的责任。金融稳定和监管合规是重中之重， 由Core 1监控。为了实现这些功能，将通过 流程描述如下： 目标1。对项目进行全面的P01管理、协调和监督。 目标2。确保及时的财务会计和报告。 目标3。确保遵守所有机构、州和联邦研究指南。 目标4。制定并实施P01沟通、出版和数据共享计划。 目标5。为所有数据分析提供统计支持。 行政核心将致力于实现这些目标和本计划项目设定的科学目标， 为了快速开发泛β CoV疫苗。

Administrative Core 1 Abstract The overall goal of this program project is to design and develop panbetacoronavirus (panbetaCoV) vaccines for group 2b and 2c betaCoVs that will be available when the next coronavirus outbreak occurs. This programproject will have four projects, an Administrative core and two supporting share resource cores. To support the success of this grant, the Administrative Core will coordinate and monitor scientific and administrative activities and ensure all projects and cores synergize and maintain all aspects of compliance with federal and state regulations. The financial management, administrative management, and sharing of resources across projects and cores will be the responsibility of this core. Financial stability and regulatory compliance is of top priority and will be closely monitored by Core 1. To achieve these functions, the following Specific Aims will be completed through the processes described below: o Aim 1. Provide overall P01 management, coordination, and supervision of the Program. o Aim 2. Ensure timely financial accounting and reporting. o Aim 3. Ensure compliance with all institutional, state, and federal research guidelines. o Aim 4. Develop and implement P01 communication, publication, and data sharing plans. o Aim 5. Provide statistical support for all data analyses. The administrative core will work to achieve these goals and the scientific goals set by this program project in order to rapidly develop pan-betaCoV vaccines.