Emory Training Program in Translational Research to End the HIV Epidemic

项目摘要 在这份题为‘埃默里终止艾滋病毒流行的翻译研究培训计划’的申请书中， 我们提出了一个新的T32培训计划，重点是位于震中的翻译艾滋病毒科学 佐治亚州亚特兰大埃默里大学美国南部的艾滋病疫情。我们的培训计划将提供2个 为5名博士后研究员提供多年支持，并为2名博士后研究生提供暑期实习机会-- 代表少数族裔(URM)学生通过实践经验和 正式的教学，并教育学员关于艾滋病毒研究的更广泛的背景，通过翻译 连续体。我们的培训计划将与重要的艾滋病毒研究充分结合并加以利用 埃默里艾滋病研究中心(CFAR)的投资组合，并跨越正在进行的艾滋病毒研究的范围 3个主要重点领域的活动：1.以实验室为基础的基础科学、疫苗和治疗研究；2. 以患者为中心的临床研究；3.公共卫生与实施学。我们的培训 该计划将包括NIH艾滋病毒/艾滋病研究优先事项中的每一项研究活动，以减少 艾滋病毒发病率，开发下一代艾滋病毒疗法，进行艾滋病毒治愈研究，以及 解决艾滋病毒相关的共病、合并感染和并发症；但更重要的是，我们的计划 还将让学员接触艾滋病毒研究和团队科学的交叉领域，以加快翻译 将发现转化为改善健康结果。我们已经组建了一支35人的团队，他们来自不同的领域，经验丰富 三个艾滋病毒研究重点领域的导师，并为我们的学员设计授课机会 补充他们的研究项目，并扩大他们对板凳到床边到社区的理解 艾滋病研究成果翻译创新。此外，我们培训计划的地理位置位于 并被卫生与公众服务部指定的重点地区中的4个县包围 结束艾滋病毒流行(EHE)倡议进一步表明，迫切需要制定和支持下一个 我们机构专门培养了一代艾滋病毒调查人员。鉴于艾滋病毒在南方流行的严重性 在全球范围内，以及提出在未来10年内结束美国艾滋病毒流行的新的国土安全部倡议， 在整个艾滋病毒研究过程中培养下一代翻译艾滋病毒科学家是至关重要的 重要性。博士后实习生将从我们的T32项目中脱颖而出，为科学独立和 对他们的研究如何适应多方向和多学科的框架有深刻的理解 以结束艾滋病毒流行为长期目标的艾滋病毒研究。

Project Abstract In this application entitled `Emory Training Program in Translational Research to End the HIV Epidemic', we propose a new T32 training program focused on translational HIV science located at the epicenter of the US HIV epidemic in the Southern US at Emory University in Atlanta, GA. Our training program will provide 2 years of support to 5 post-doctoral fellows and a summer internship opportunity for 2 pre-doctoral under- represented minority (URM) students to conduct cutting-edge HIV research through hands-on experience and formal didactics and also educate trainees on the broader context of HIV research across the translational continuum. Our training program will be fully integrated with and capitalize on the significant HIV research portfolio of the Emory Center for AIDS Research (CFAR) and span the spectrum of ongoing HIV research activities in 3 major areas of focus: 1. Laboratory-based basic science, vaccine, and cure research, 2. Patient-centered clinical research, and 3. Public health and implementation science. Our training program will encompass research activities in each of the NIH HIV/AIDS research priorities to reduce the incidence of HIV, develop next generation HIV therapeutics, conduct research towards an HIV cure, and address HIV associated co-morbidities, co-infections and complications; but, more importantly, our program will also expose trainees to cross-cutting areas of HIV research and team science to accelerate the translation of discovery into improved health outcomes. We have assembled a team of 35 diverse and experienced mentors across the 3 HIV research focus areas and designed didactic opportunities for our mentees to complement their research projects and expand their understanding of bench to bedside to community translation of HIV research innovation. In addition, the geographic position of our training program located in and surrounded by 4 of the counties named as focus areas for the Department of Health and Human Services Ending the HIV Epidemic (EHE) initiative further demonstrates the urgency to develop and support the next generation of HIV investigators specifically at our institution. Given the gravity of the HIV epidemic in the South and globally and the new DHHS initiative that proposes to end the US HIV epidemic in the next 10 years, fostering the next generation of translational HIV scientists across the HIV research continuum is of utmost importance. Post-doctoral trainees will emerge from our T32 program ready for scientific independence and with a deep understanding of how their research fits into the multidirectional and multidisciplinary framework of HIV research with the long-term goal of ending the HIV epidemic.