Interrupting the Intergenerational Transmission of Traumatic Stress: Identifying Parental Targets for Intervention by Looking Under the Skin

项目摘要/摘要 父母的精神病理，包括创伤应激，对儿童的 发展和提高他们在需要时受益于循证心理健康服务的能力。小孩儿 干预措施要求父母对儿童的痛苦和挑战有具体和可控的反应 这些行为，然而正是这些时刻唤起了父母的负面情绪。情绪化 造成创伤应激和相关障碍的调节失调可能是导致儿童这种障碍的原因。 发展和对治疗的反应，因此，关于父母情绪调节(ER)的更精细的工作是 这是非常需要的。 拟议的研究和培训将侧重于加强该领域的情感知识 经历过创伤的父母的过程和对干预的反应。这是一个特别的 研究父母ER的重要人群，因为创伤应激的情绪症状多种多样， 从愤怒到恐惧再到情绪麻木，而且经常出乎意料地出现。拟议的研究将 使用神经生理学评估(EEG)来阐明情绪唤醒、动机和调节 N=60位在童年经历过人际关系创伤的父母， 目前有学龄前儿童(3至6岁)。该项目设计将包括一项临床试验和 使用脑电生物标记物来衡量对创伤告知的父母干预计划的反应。 以便进行拟议的研究，并为下一阶段的HER做好准备 作为一名独立科学家的职业生涯，拟议的培训提供了来自非凡导师的指导 团队在以下目标中：(1)提高知识深度和情感概念化，养育子女，以及 通过将生物行为和面向过程的二元模型应用于这项工作(2)扩展深度 和广度的心理生理学方法的知识和技能，(3)培养指挥能力 翻译科学应用阶段的独立研究，(4)加强方法论和统计学 (5)增加写作和出版的机会和技能。 拟议的培训将支持应聘者从事翻译工作的长期职业目标 它将对父母情绪过程的新颖的基础研究与儿童和家庭的应用工作相结合 复原力，其最终目标是防止创伤应激的代际传播。

PROJECT SUMMARY/ABSTRACT Parental psychopathology, including traumatic stress, presents significant risk to children’s development and to their ability to benefit from evidence-based mental health services when needed. Child interventions require parents to have specific and controlled responses to child distress and challenging behaviors, yet these are the very moments that evoke negative emotions in parents. The emotional dysregulation that underlies traumatic stress and related disorders may account for this hindrance in child development and response-to-treatment, and thus, more refined work on parent emotion regulation (ER) is sorely needed. The proposed research and training will focus on enhancing the field’s knowledge of emotional processes and response-to-intervention in parents who have experienced trauma. This is a particularly important population in which to study parental ER, as the emotional symptoms of traumatic stress are diverse, ranging from anger to horror to emotional numbing, and often arise unexpectedly. The proposed research will use neurophysiological assessment (EEG) to elucidate emotional arousal, motivation, and regulatory processes in N = 60 parents who experienced interpersonal trauma during their own childhoods, and who currently have preschool-aged children (3- to 6-year-olds). The project design will include a clinical trial and use of EEG biomarkers to measure response to a trauma-informed parenting intervention program. In order to conduct the proposed research and to prepare the candidate for the next phase of her career as an independent scientist, the proposed training provides guidance from an exceptional mentorship team in the following goals: (1) enhance depth of knowledge and conceptualization of emotion, parenting, and traumatic stress by applying biobehavioral and process-oriented, dyadic models to this work (2) expand depth and breadth of knowledge and skills in psychophysiological methods, (3) develop the ability to conduct independent research in the applied stages of translational science, (4) augment methodological and statistical skills, and (5) increase opportunities for and skills in manuscript-writing and publication. The proposed training will support the candidate’s long-term career goal to conduct translational work that integrates novel, basic research on parental emotional processes with applied work on child and family resilience, with the ultimate goal of preventing the intergenerational transmission of traumatic stress.