Iowa Cochlear Implant Clinical Research Center - VIII

项目主任/首席调查员(最后、第一、中间)：甘茨，布鲁斯·J 项目摘要--核心B 核心B的主要职责是吸引受试者；为这些人提供临床服务 受试者；维护人工耳蜗(CI)研究登记；监测术后剩余听力；以及获得 将在研究项目中使用的听力学和言语感知结果测量。核心B将 还为所有调查人员提供技术和统计支持。这四个研究项目具有很高的 相互依存、相互关联的。每个项目都依赖于其他项目生成的数据来解决其 具体目标，使用相似的受试者群体来解决爱荷华州人工耳蜗术临床研究 中心(红十字委员会)的总体目标。 这里描述的是(1)科目应计所需的广泛的术前评估；(2)具体的 要研究的人群；(3)要使用的顺位；(4)基本的听力和言语知觉结果测量 将从受试者那里获得的表演；(5)受试者参与的时间线。整体而言 还讨论了统计设计、数据管理和技术支持。各个项目描述了 具体的研究问题，以及每个项目如何相互作用和相互依赖。

Program Director/Principal Investigator (Last, First, Middle): Gantz, Bruce J. PROJECT SUMMARY – CORE B Core B's primary responsibilities are to accrue a subject population; provide the clinical service for these subjects; maintain a cochlear implant (CI) research registry; monitor postoperative residual hearing; and obtain audiologic and speech perception outcome measures that will be used in the research projects. Core B will also provide the technical and statistical support for all investigators. The four research projects are highly interdependent and interrelated. Each project depends on data generated by the others to address their specific aims, using similar subject populations to address the Iowa Cochlear Implant Clinical Research Center's (ICICRC) overall goals. Described here are (1) extensive preoperative evaluations required for subject accrual; (2) specific populations to be studied; (3) CIs to be used; (4) basic audiologic and speech perception outcome measures of performance that will be obtained from subjects; and (5) the time-line of subject involvement. The overall statistical design, data management and technical support are also discussed. The individual projects describe the specific research questions and how each project is interactive and dependent on the others.