Accelerating paediatric cancer precision medicine with mass spectrometry-based proteomics

儿童零癌症(Zero)计划测量单个癌症样本中的DNA和RNA，然后为每个儿童推荐独特的治疗计划。在这项研究中，我们将测量儿童医学研究所ProCan的大约100个零癌症样本中的蛋白质组(即蛋白质组)。该项目的目标是评估蛋白质数据对于指导药物治疗建议和为被诊断为预后较差的癌症儿童寻找新的药物靶点的价值。

The Zero Childhood Cancer (ZERO) Program measures the DNA and RNA in individual cancer samples and then recommends a unique treatment plan for each child. In this study, we will measure the proteome (ie the set of proteins) in ~100 ZERO cancer samples at the Children's Medical Research Institute's ProCan. The goal of this project is to assess the value of protein data for informing drug treatment recommendations and finding new drug targets for children diagnosed with a cancer of poor prognosis.