Identifying infection-induced determinants of paediatric acute lymphoblastic leukaemia progression

确定感染诱发的儿童急性淋巴细胞白血病进展的决定因素

• 批准号: 369875
• 负责人: Reid Gregor
• 金额: $ 50.16万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-09-01 至 2022-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=369875&lang=en
• 关键词: Acute Lymphoblastic Leukemia; Early-Life Infection; Mouse Models Of Cancer; Neonatal Immunity; Pediatric Cancer

Epidemiology studies have frequently identified associations between early-life infections and risk of childhood leukemia. However, both leukemia-promoting and protective effects have been reported and as yet no mechanism has been identified to explain th

流行病学研究经常发现早期感染与儿童白血病风险之间的关联。然而，白血病促进和保护作用都有报道，但至今还没有确定机制来解释这一现象。