Molecular, Cellular, and Developmental Mechanisms

项目摘要/摘要 在21世纪，知识、研究技术和分析工具的进步创造了 我们对生物学基本原理的理解获得重大突破的前所未有的机遇 以及它们的潜在机制。我们在这里提出了一个新的跨学科的计划，在分子，细胞和 哈佛医学院(HMS)的发展机制(MCDM)将建立在我们最近的投资基础上 在科学基础设施、教育和培训方面。我们的目标是培养一个多元化、严谨、独立的 一群科学家，他们将在机械生物学中发现新的基本问题并开发精辟的工具 感谢你向他们致敬。在我们成功的前身T32项目的基础上，我们计划招聘20名学员 每年从生物和生物医学科学伞形学院研究生二年级开始 程序。这20名受训人员将分布在一组80个MCDM教官实验室。我们的方法是 培养一支富有弹性和创造力的学者群体将既以证据为基础，又以学生为中心。我们会 将创新节目带给一群才华横溢的实习生。通过持续改进 在导师实践、社区参与和包容方面，我们将促进 做好充分准备，为生命科学研究做出自信和变革性贡献的学者 许多与研究相关的职业需要转化关于基本生物机制的新发现 进入生物医学和生命科学应用领域。

Project Summary/Abstract In the 21st century, advances in knowledge, research technologies, and analytical tools have created unprecedented opportunities for major breakthroughs in our understanding of fundamental biological principles and their underlying mechanisms. We propose here a new interdisciplinary program in Molecular, Cellular, and Developmental Mechanisms (MCDM) at Harvard Medical School (HMS) that will build on our recent investments in science infrastructure, education, and training. Our goal is to educate a diverse, rigorous, and independent group of scientists who will identify novel essential questions in mechanistic biology and develop incisive tools for addressing them. Based on our successful predecessor T32 program, we plan to recruit a group of 20 trainees per year beginning in their second year of graduate study from the Biological and Biomedical Sciences umbrella program. These 20 trainees will distribute across a group of 80 MCDM preceptor laboratories. Our approach to cultivating a resilient and creative group of scholars will be both evidence-based and student-centered. We will bring innovative programming to an exceptionally talented pool of trainees. Through continuous improvements in mentorship practice, community engagement and inclusion, we will foster a collaborative community of scholars who are well-prepared to make confident and transformative contributions to life science research and the many research-related careers needed to convert new discoveries about fundamental biological mechanisms into biomedical and life-sciences applications.