Population Sciences and Health Disparities Program

人口科学和健康差距计划(PSHD) 项目摘要/摘要 人口科学和健康差距方案(PSHD)的中心主题是进行有影响力的 加州大学戴维斯综合癌症中心预防和/或减轻癌症负担的研究 (UCDCCC)集水区及更远地区。该计划汇集了基础科学家、生物统计学家、 流行病学家、健康差距研究人员和临床医生共同研究影响癌症发生的因素 在人类人群中，目标是降低可避免的癌症发病率、发病率、死亡率，并改善 受癌症影响的人(即幸存者及其家人)的生活质量。PSHD有两个具体目标 这就框定了其成员的研究贡献并将其联系在一起。目标1是发现癌症的病因 发生和晚期疾病，以减轻健康差距。目标2是评估决定因素和 干预措施，以改善癌症结果，并为循证实践提供信息。Theresa Keegan，博士，硕士 (癌症流行病学家)和Diana Miglioretti博士(生物统计学家)是PSHD的联合领导人。该计划的 研究范围涵盖癌症控制连续体，从癌症病因、初级预防、筛查、 以及诊断、治疗、监测和结果研究。PSHD有4名成员中的17名正式成员 学校/学院和加州大学戴维斯分校的八个系。PSHD与癌症相关的资金总额为每年590万美元 直接成本，包括320万美元的同行评审和140万美元的NCI资金。出版物总数为 其中20%是方案内的，24%是方案间的，66%是多机构的，21%是出版的 发表在影响力很大的期刊上。美国疾病控制与预防中心部署了增加癌症相关资金的措施，包括 战略招聘两名高级教员，他们将为该计划带来新的团队科学补助金。 此外，UCDCCC为PSHD提供酌情资金支持，为其领导层提供 有能力支持更多的试点项目，以提高该方案的影响力。

POPULATION SCIENCES AND HEALTH DISPARITIES PROGRAM (PSHD) PROJECT SUMMARY/ABSTRACT The central theme of the Population Sciences and Health Disparities Program (PSHD) is to conduct impactful research to prevent and/or reduce the cancer burden in the UC Davis Comprehensive Cancer Center (UCDCCC) catchment area and beyond. The Program brings together basic scientists, biostatisticians, epidemiologists, health disparities researchers, and clinicians to study the factors that affect cancer occurrence in human populations with the goal of reducing avoidable cancer incidence, morbidity, mortality, and to improve the quality of life for those affected by cancer (i.e., survivors and their families). PSHD has two Specific Aims that frames and ties its member’s research contributions. Aim 1 is to discover etiological factors for cancer occurrence and advanced disease to mitigate health disparities. Aim 2 is to evaluate determinants and interventions to improve cancer outcomes and inform evidence-based practices. Theresa Keegan, PhD, MS (cancer epidemiologist) and Diana Miglioretti, PhD (biostatistician) are co-leaders for PSHD. The Program’s research portfolio spans the cancer control continuum, from cancer etiology, primary prevention, screening, and diagnosis, to treatment, surveillance, and outcomes research. PSHD has 17 full members from four schools/colleges and eight departments at UC Davis. PSHD’s total cancer relevant funding is $5.9M annual direct cost, including $3.2M in peer-reviewed and $1.4M in NCI funding. The total number of publications is 438 of which 20% are intra-programmatic, 24% inter-programmatic, 66% multi-institutional, and 21% published in high impact journals. The UCDCCC has deployed measures to increase cancer-related funding including the strategic recruitment of two senior faculty members who will bring new team science grants to the Program. Additionally, the UCDCCC provides discretionary funding support to the PSHD, providing its leadership the ability to support more pilot projects that will enhance the Program’s impact.