Discovery to Commercialization Program for Substance Abuse Prevention and Treatment (D2C: SAPT)

项目摘要 在物质使用障碍(SOD)方面投资严重不足，并继续依赖于 同样的方法并不奏效。在这项提案中，我们积极寻求支持颠覆性创新，以 遏制肥皂水的上涨趋势，刺激进步。这样的干扰最有可能来自于 积极致力于肥皂泡的治疗和知识的发展。但许多有能力这样做的人并不知道 发现商业化的或看到其商业化价值的。我们的首要目标是让更多的基础科学家认为 像企业家一样，并能够获得他们参与商业化所需的资源 流程。通过我们建议的任务，我们将开发和提供经过策划的创业教育 对于基础科学研究人员来说，为他们提供将发现商业化所需的工具， 颠覆性地创新，推进肥皂泡的预防、诊断和治疗。 药物滥用预防和治疗的发现商业化计划 (D2C：SAPT)课程将在这项为期5年的拨款期间系统地开发、实施和评估 句号。拟议倡议的基石是在约翰斯中学颁发新的创业证书 霍普金斯大学凯里商学院(AIM 2)。这个项目将利用我们在教学方面的经验 为约翰·霍普金斯大学的科学家提供创业精神，并为研究人员量身定做。异步者 为证书计划开发的在线模块将广泛分发(目标1)，并通过我们的 我们将有意识地建立(目标3)和多样化(目标4)能够支持的社区的教育努力 将发现转化为市场和影响肥皂水。 这将是一个专门的项目，面向所有职业层次的科学家，即 以理论框架为基础，辅以与企业家相关的专业教育 身份形成和社区建设。D2C：SAPT将由三部分组成：异步模块 包括构思、市场发现、知识产权、监管战略、商业和 财务建模，为期数天的面对面研讨会，包括在南德诊所的观察、对话 与利益相关者、设计和原型制作，以及指导的体验式学习组件最终形成 投球比赛。该项目的毕业生将有能力申请翻译资金、专利和许可证 知识产权或发射公司。更广泛地说，他们将成为一个大型虚拟社区的一部分 研究人员和实践者，并将在改变学术科学家的文化方面发挥作用。使用一个 敏锐地了解南德领域存在的差距，可能的创新类型，以及 培训科学家将他们的发现推向市场所需的过程，该培训计划将 通过促进启动将南达科他州临床实践转移到 下一代解决方案。

Project Summary There has been critical underinvestment in Substance Use Disorders (SUDs) and continuing to rely on the same approaches is not working. In this proposal, we actively seek to support disruptive innovations to stem the rising tide of SUDs and stimulate progress. Such disruptions are most likely to come from those actively engaged in treating and advancing knowledge of SUDs. But many in a position to do so are not aware of or see value in discovery commercialization. Our overarching goals are to have more basic scientists think like entrepreneurs and to have access to the resources they need to engage in the commercialization processes. Through our proposed tasks, we will develop and deliver entrepreneurship education that is curated for basic science researchers, empowering them with the tools they need to commercialize their discoveries, disruptively innovate, and advance the prevention, diagnosis, and treatment of SUDs. The Discovery to Commercialization Program for Substance Abuse Prevention and Treatment (D2C: SAPT) curriculum will be systematically developed, implemented, and evaluated during this 5-year grant period. The cornerstone of the proposed initiative is a new Certificate in Entrepreneurship at the Johns Hopkins University Carey Business School (Aim 2). This program will leverage our experience in teaching entrepreneurship to scientists at Johns Hopkins and be customized to SUD researchers. The asynchronous online modules developed for the certificate program will be distributed widely (Aim 1), and through our educational efforts we will intentionally build (Aim 3) and diversify (Aim 4) the community that can support translation of discovery to market and impact SUDs. This will be a specialized program for SUD researchers aimed at scientists at all career levels that is grounded in theoretical frameworks and complemented by professional education related to entrepreneur identity formation and community building. D2C: SAPT will comprise three parts: asynchronous modules consisting of topics in ideation, market discovery, intellectual property, regulatory strategy, business, and financial modeling, an in-person multi-day workshop comprising observations in SUD clinics, conversations with stakeholders, design, and prototyping, and a mentored experiential learning component culminating in a pitch competition. Program graduates will be equipped to apply for translational funding, patents, and to license intellectual property or launch companies. More broadly, they will be part of a large virtual community of researchers and practitioners and will play a role in transforming the culture of academic scientists. With a keen understanding of the gaps that exist in the SUD field, the types of innovations that are possible, and the process needed to train scientists in moving their discoveries to market, this training program will have substantial public health impact by facilitating the launch of projects that move clinical practice in SUD to the next generation of solutions.