Sexually Transmited Infection Testing Risk and Prevention among Trans Women (STRiP-T)

项目摘要/摘要 职业目标：我的长期职业目标是：a)获得全职终身教职；b) 成为人类免疫缺陷病毒/性传播感染(艾滋病毒/性传播感染)的独立调查员 跨性别妇女(跨性别妇女、出生时被指定为男性的妇女)的风险和预防研究。这 研究和培训基金将为我提供一个机会来提高我作为博士后的研究技能 中佛罗里达大学的一名学者，并成功过渡到一名性传播感染干预科学家 解决变性妇女面临的突出的健康不平等问题。职业发展：这项K99/R00研究 和培训计划将促进我努力获得评估可行性所需的高级培训， 用于STI检测和临床医生采集样本的可接受性和有效性 考察综合社会空间网络特征之间的关系(例如，社会资本、获取 护理)和变性妇女中的性传播感染风险。在K99阶段，我的训练目标包括a)混合方法 通过获得定性研究和分析方面的技能进行研究；b)干预绘图；c)社会和空间 流行病学方法，通过获得社会网络分析和地理信息系统方面的技能。 研究目标：此K99/R00应用程序建议整合我以前在稳健量化方面的经验 方法具有混合方法研究、干预地图和社会与空间方面的新知识 流行病学方法，以增强我作为一名专注于解决STI健康问题的研究人员的独立性 保健环境中的差异，这是国家少数民族健康和健康差异研究所 (NIMHD)已将其确定为主要优先事项。具体目标：目标1：进行试点研究，以探索可接受性， 生殖器和非生殖器样本自采集与临床采集的可行性和有效性 患有和不患有新阴道感染的妇女使用混合方法检测性传播感染(定量调查和深度调查 采访)。目的2：检查多部位(生殖器、直肠、咽部)性传播感染在患有和 没有新的病毒。目标3：描述社会和空间网络特征之间的关系(例如， 网络规模、社会支持、社区特征)和变性妇女的性传播感染风险 新天鹅。导师团队：我的努力将由一个有成就的、跨学科的导师团队来指导 (有过一起工作的经验)致力于支持我向独立调查员过渡。

PROJECT SUMMARY/ABSTRACT Career Goal: My long-term career goals are to a) secure a full-time tenure track academic appointment; and b) become an independent investigator in human immunodeficiency virus/sexually transmitted infection (HIV/STI) risk and prevention research among transgender women (trans women, women assigned male at birth). This research and training grant will provide me with the opportunity to enhance my research skills as a Postdoctoral Scholar at the University of Central Florida and to successfully transition to an STI intervention scientist that addresses prominent health inequalities faced by trans women. Career Development: This K99/R00 research and training plan will catalyze my efforts to acquire the advanced training necessary to assess the feasibility, acceptability, and validity of self-collected samples versus clinician collected samples for STI testing and examine the relationship between combined socio-spatial network characteristics (e.g., social capital, access to care) and STI risk among trans women. During the K99 phase my training goals consist of a) mixed methods research, by gaining skills in qualitative research and analysis; b) intervention mapping and c) social and spatial epidemiology methods, by gaining skills in social network analysis and geographic information systems. Research Objective: This K99/R00 application proposes to integrate my prior experience in robust quantitative methods with new knowledge in mixed methods research, intervention mapping and social and spatial epidemiology methods in order to enhance my independence as a researcher focused on addressing STI health disparities within a health care setting, which the National Institute on Minority Health and Health Disparities (NIMHD) has identified as a major priority. Specific Aims: Aim 1: Conduct pilot study to explore the acceptability, feasibility, and validity of self-collected vs. clinician collected genital and non-genital samples among trans women with and without neovaginas to detect STIs using mixed methodology (quantitative surveys and in-depth interviews). Aim 2: Examine multi-site (genital, rectal, pharyngeal) STI prevalence among trans women with and without neovaginas. Aim 3: Characterize the relationship between social and spatial network characteristics (e.g., network size, social support, neighborhood characteristics) and STI risk among trans women with and without neovaginas. Mentorship team: My efforts will be guided by an accomplished, interdisciplinary team of mentors (with prior experience working together) committed to support my transition to an independent investigator.