LOTUS: An mHealth Intervention to Improve HIV Prevention Service Engagement and Intersectional Stigma among Racially Diverse Women Who Use Drugs

项目摘要/摘要 候选人。Meyers-Pantele博士申请K01指导培训奖，目标是独立的职业生涯 作为一名健康行为干预者，实现多产和独立的研究生涯，专注于 减少吸毒妇女之间的艾滋病毒差距(WWUD)。然而，她目前的训练并非如此 超越了对污名和物质使用数据的二级分析，不足以进行深入研究 关于制定和实施卫生保健所需的理论和实践方法的指导 针对种族和民族多样性的WWUD的行为干预。具体地说，K01培训将支持她 通过以下方式过渡到独立的职业科学家：(1)熟练掌握交叉性理论以提供 针对不同种族的艾滋病毒预防服务参与度和跨部门污名的干预措施 WWUD，(2)获得mHealth干预设计和开发方面的专业知识，以创建拟议的mHealth 干预，(3)培养熟练程度，实施随机对照试验，试行已开发的 干预，(4)加强她在实施科学方面的技能基础，以设计具有 采用和实施的潜力，以及(5)培养必要的个人发展技能 成功的学术生涯。这些培训目标将通过授课课程、培训 研讨会、参与专业研究网络、实践研究和指导培训。 研究与环境。WWUD感染艾滋病毒的风险增加，接触前水平较低 预防是知识和接受。此外，种族和民族多样化的WWUD体验 由于性别和种族主义的社会规范围绕着妇女、母亲、 道德、物质使用和犯罪行为，所有这些都对妇女参与 艾滋病毒预防服务。移动健康(MHealth)干预措施和针对跨部门 耻辱具有增加艾滋病毒预防服务参与度的潜力，但缺乏干预措施。 为种族多元化的WWUD量身定做。拟议的研究将为Meyers-Pantele博士提供 开展培训，以解决艾滋病毒预防研究中的这一关键差距。她将使用定性的方法来确定 艾滋病毒预防服务和跨部门耻辱方面的主要经验，以及潜在的障碍和促进者 对干预措施的采纳和实施，为潜在的理论驱动的移动健康的发展提供信息 干预组件。这些信息将用于开发和测试mHealth的可用性 减少污名干预(LOTUS)干预，以改善艾滋病毒预防服务参与度和 对种族和民族多元化的WWUD的跨界别污名。最后，她将进行一项试验性随机对照试验，以评估 莲花干预的可行性、可接受性和初步影响。这次培训将是独一无二的 将她定位为加州大学圣地亚哥分校为数不多的专门研究WWUD交叉耻辱的mHealth干预者之一。

PROJECT SUMMARY/ABSTRACT Candidate. Dr. Meyers-Pantele applies for this K01 mentored training award with the independent career goal of attaining a productive and independent research career as a health behavior interventionist focused on reducing HIV disparities among women who use drugs (WWUD). Her current training, however, does not extend beyond the secondary analysis of stigma, and substance use data, and is insufficient for in-depth instruction on the theoretical and practical methods required for the development and implementation of health behavior interventions for racially and ethnically diverse WWUD. Specifically, the K01 training will support her transition to an independent career scientist by: (1) developing proficiency in intersectionality theory to inform an intervention targeting HIV prevention service engagement and intersectional stigma for racially diverse WWUD, (2) gaining expertise in mHealth intervention design and development to create the proposed mHealth intervention, (3) building proficiency in the implementation of randomized controlled trials to pilot the developed intervention, (4) strengthening her skill base in implementation science to design an intervention that has the potential for adoption and implementation, and (5) fostering the personal development skills necessary for a successful academic career. These training aims will be accomplished through didactic courses, training workshops, participation in professional research networks, hands-on research, and mentored training. Research and Environment. WWUD are at increased risk for HIV and have low levels of pre-exposure prophylaxis knowledge and acceptance. Additionally, racially and ethnically diverse WWUD experience intersectional stigma due to gendered and racialized social norms surrounding womanhood, motherhood, morality, substance use, and criminality, all of which have important implications for women’s engagement with HIV prevention services. Mobile health (mHealth) interventions and interventions that target intersectional stigma have the potential to increase HIV prevention service engagement, but there is a dearth of interventions tailored toward racially diverse WWUD. The proposed research will provide Dr. Meyers-Pantele with the training to address this critical gap in HIV prevention research. She will employ qualitative methods to identify key experiences with HIV prevention services and intersectional stigma, and potential barriers and facilitators to intervention adoption and implementation, to inform the development of potential theory-driven mHealth intervention components. This information will be used to develop and test the usability of the mheaLth interventiOn To redUce Stigma (LOTUS) intervention to improve HIV prevention service engagement and intersectional stigma for racially and ethnically diverse WWUD. Lastly, she will conduct a pilot RCT to assess the feasibility, acceptability, and preliminary impact of the LOTUS intervention. This training will uniquely position her as one of few mHealth interventionists specializing in intersectional stigma for WWUD at UCSD.