Administrative Core - EPIC

项目摘要 真核病原体在全球范围内引起重大疾病，并在更多的地方威胁到南方公民的健康。 卡罗莱纳和美国东南部。克莱姆森大学在真核病原体研究方面的实力 领导克莱姆森大学董事会批准成立真核病原体创新 中心（EPIC）于2013年1月。EPIC的首要主题是研究全球重要的真核生物 病原体使用最先进的分子、细胞、生物化学、遗传、化学、生物物理和基因组 接近。行政核心提案的具体目标是：（1）继续建设克莱姆森EPIC 成为一个国家和国际公认的研究中心，（2）招募高素质的教师与多样化 研究兴趣，以建立临界质量和扩大EPIC的广度，（3）开发和管理一个 全面的指导计划，以提高目标研究者（TI）在研究和资助方面的成功。 实现这些目标的三个关键方法是：（i）通过雇用更多的专业人员来扩大专业知识的广度， 教师和博士后研究人员在该地区的真核生物发病机制，并为他们提供 全面和深入的研究和培训指导，为他们提供工具， 成功竞争NIH R 01或同等资金;（ii）继续主持顶级研究人员的演讲 在真核病原体会议的细胞生物学领域，并在中心/部门/学院 举办研讨会，以提高EPIC的知名度;及（iii）加强EPIC和克莱姆森之光的研究基础设施 成像设施和克莱姆森大学基因组学和生物信息学核心设施，以协助研究 企业. EPIC行政核心的总体规划结合了 理学院和克莱姆森大学管理部门将使EPIC真正实现这一地位 卓越生物医学研究中心

PROJECT SUMMARY Eukaryotic pathogens cause significant disease globally, and more locally, threaten the health of citizens in South Carolina and the Southeastern United States. Clemson University’s strength in eukaryotic pathogens research led the Clemson University Board of Trustees to approve formation of the Eukaryotic Pathogens Innovation Center (EPIC) in January 2013. The overarching theme of EPIC is the study of globally important eukaryotic pathogens using state-of-the-art molecular, cellular, biochemical, genetic, chemical, biophysical, and genomic approaches. The Specific Aims of the Administrative Core proposal are: (1) to continue building Clemson EPIC into a nationally and internationally recognized research center, (2) to recruit high quality faculty with diverse research interests to build critical mass and expand the breadth of EPIC, and (3) to develop and administer a comprehensive mentoring program to enhance Target Investigator (TI) success in research and grantsmanship. Three key approaches to achieving these aims are: (i) expanding the breadth of expertise by hiring additional faculty and postdoctoral researchers in the area of eukaryotic pathogenesis and providing them with comprehensive and intensive mentoring in research and grantsmanship to provide them with the tools to successfully compete for NIH R01 or equivalent funding; (ii) continuing to host presentations by top researchers in the field at the Cellular Biology of Eukaryotic Pathogens meeting and at Center/Departmental/College seminars to raise EPIC’s profile; and (iii) enhancing research infrastructure within EPIC and the Clemson Light Imaging Facility and the Clemson University Genomics and Bioinformatics core facilities to aid in the research enterprise. The overall plan for the EPIC Administrative Core combined with the demonstrated commitment of the College of Science and the Clemson University Administration will position EPIC to truly achieve the status of a Center for Biomedical Research Excellence.