Instrumentation, Fabrication, and Design Core

视觉科学的仪器和制造核心资源， 罗纳德西尔弗曼，核心总监 总结/摘要 核心的长期目标是为视觉研究提供机械设计和制造支持， 哥伦比亚，特别是研究人员与RO 1赠款和年轻的研究人员收集数据，为他们的 第一次成功的RO 1最先进的视觉研究取决于新的视觉研究的发展。 技术和现有技术的改进。核心支持一个特别专用的机器 商店和一个机械师。因为车间是内部的，机械师熟悉视觉的要求， 研究，设计新的设备是远远更有效的比它会与大学或商业 店核心有四个具体目标：1）设计和建造视觉所需的定制设备 研究，包括系统神经科学视觉研究和眼科科学。（2）提供应急 维修和改装目前用于视觉研究的设备。（3）培养学生， 博士后研究员以最有效的方式与仪器设计师合作。4）鼓励 视觉研究调查人员之间的合作，让他们分享新设备的想法， 在多个实验室中使用。这对于系统神经科学视觉研究尤其重要， 类似的设备被用来回答截然不同的科学问题。仪器设计中的协作 往往导致科学合作。核心构建了用于系统神经科学的标准设备 比如录音室、灵长类椅子和网格。虽然其中一些设备是可用的 从商业上来说，内核建造的那些更耐用。定制设备的例子 核心是安装在笼子里的行为训练系统，用于在笼子里训练猴子，而不是使用 钻机时间;一个系统，用于提升猴椅到笼子开口，以方便从笼子转移到 椅子;用于大鼠眼睛血流研究的3D超声探头操纵器。这个成功的原型 将被扩大用于人类。

Instrumentation and Fabrication Core Resource for Vision Sciences, Ronald Silverman, Core Director Summary/Abstract The long-term goal of the Core is to provide mechanical design and fabrication support for vision research at Columbia, especially that of investigators with RO1 grants and young investigators gathering data for their first successful RO1s. State-of-the-art vision research is dependent upon the development of new technology and the improvement of current technology. The Core supports a specially dedicated machine shop and one machinist. Because the shop is in-house, and the machinist is familiar with demands of vision research, designing new equipment is far more efficient than it would be with a University or commercial shop. The core has four specific aims: 1)To design and build custom equipment necessary for vision research, both systems neuroscience vision research and ophthalmic science. 2)To provide emergency repairs and modifications for equipment currently in use for vision research. 3)To train students and postdoctoral fellows in the most effective ways to collaborate with instrument designers. 4)To encourage collaboration among vision research investigators, having them share ideas for new devices that might be used in multiple laboratories. This is especially important for systems neuroscience vision research, where similar equipment is used to answer vastly different scientific questions. Collaboration in instrument design has often led to scientific collaboration. The Core builds the standard devices used for systems neuroscience such as recording chambers, primate chairs and grids. Although some of these devices are available commercially, the ones built by the Core are far more durable. Examples of custom equipment built by the Core are cage mounted behavioral training systems to train monkeys in their home cage rather than using rig time; a system for lifting a monkey chair to the cage opening to facilitate transfer from the cage to the chair; a 3D ultrasound probe manipulator for blood flow studies in rat eyes. This now successful prototype will be expanded for use in humans.