NICHD HUMAN BIOSPECIMEN REPOSITORY – MPIDB PHACS HOPE SPECIMEN

母婴传染病科(MPIDB)促进研究，以调查艾滋病毒、其并发症和其他重大传染病对婴儿、儿童、青少年以及怀孕和非怀孕妇女的影响和治疗。这包括主要在两个主要网络进行的签约临床研究活动，这些网络积极收集标本，存放在NICHD储存库中。这些是儿科艾滋病毒艾滋病队列研究(PHACS)。 PHACS是一项总部设在美国的多中心计划，跟踪调查围产期感染艾滋病毒的青年和感染艾滋病毒/未感染艾滋病毒的婴儿、儿童和青年。PHACS目前包括四个主要方案和四个子研究。在18个SMARTT(艾滋病毒感染妇女所生的未感染艾滋病毒的儿童的抗逆转录病毒药物毒性监测研究)和14个需要资料库服务的当前研究地点AMP(青少年主协议)收集了各种类型的标本。 《关于怀孕和接触艾滋病毒/抗逆转录病毒药物的健康结果》(HOPE)探讨了包括怀孕在内的生殖健康选择和包括生殖健康结果在内的总体健康结果。希望为感染艾滋病毒的妇女及其家人提供了一个机会，让他们了解未来的进展。

The Maternal and Pediatric Infectious Disease Branch (MPIDB) promotes research to investigate the impact and treatment of HIV, its complications, and other significant infectious diseases in infants, children, adolescents, and pregnant and nonpregnant women. This includes contracted clinical research activities conducted primarily in two major networks that actively collect specimens to be housed in the NICHD repository. These are the Pediatric HIV AIDS Cohort Study (PHACS). PHACS is a multicenter United States-based program that follows both perinatally HIV-infected youth and HIV-exposed/uninfected infants, children, and youth. PHACS currently includes four main protocols and four sub studies. A wide variety of specimen types are collected at 18 SMARTT (Surveillance Monitoring for ART Toxicities Study in HIV-uninfected Children Born to HIV-infected Women) and 14 AMP (Adolescent Master Protocol) current study sites that require repository services. The Health Outcomes around Pregnancy and Exposure to HIV/ARVs (HOPE) explores reproductive health choices, including pregnancy, and overall health outcomes, including reproductive health outcomes. HOPE provides the opportunity to inform future advancements for women living with HIV and their families.