Designing and Implementing an Equity Planning Tool for International Research Partnerships

摘要 福格蒂国际中心站在推动美国国立卫生研究院(NIH)支持 促进全球健康和减轻疾病负担的国际研究。这项任务的很大一部分是 与成功地建立和维持各机构之间的国际伙伴关系有关 中低收入国家(LMIC)和高收入国家(HIC)的研究小组。权益 在LMIC和HIC研究伙伴之间--定义为确定互利投入的优先顺序， 过程、产出、结果和影响--是实现以下目标所必需的伦理和实践要求 这些伙伴关系的有意义的科学目标和成果在一个本质上不公平的世界中发挥作用。 尽管建立正式的公平做法和若干建议和准则很重要 可用于这样做的工具、系统地承认现有伙伴关系不平等的工具和方法 克服它们并没有得到很好的描述。 这项建议的目标是开发和试点一个实用的股权规划工具，使用经验丰富的艾滋病毒- 乌干达作为LMIC与美国(HIC)之间有重点的研究伙伴关系，作为案例系列 鉴于过去40年艾滋病毒流行在全球卫生研究范式中的主导地位，以及 继续将重点作为乌干达和美国许多研究伙伴关系的优先事项。这将会实现的 通过对这些伙伴关系进行解释性的定量到定性的评估，从而产生全面的 了解最佳做法和公平研究做法的障碍(目标1)。这些结果将告诉我们 创建一个由结构化调查和焦点小组材料组成的股权规划工具，以 系统地评估国际研究伙伴关系，并创建一份总结报告，强调 示范实践，确定可行的改进领域，产生可实现的计划级公平目标， 并制定实现这些目标的行动计划(目标2)。然后，股权规划工具将具有前瞻性 在研究伙伴关系内试行和评估有效性、可行性和可接受性(目标3)。 总的来说，这项提议试图阐明一种工具，以识别并纠正与股权有关的问题，这一点很重要 并在国际研究伙伴关系内推动项目层面的变革。这款K01将为Dr. 切尔西·莫德林接受了她所需的高级质量和人种学方法方面的培训，包括 国际研究伦理中的反身性、经验性和应用性方法，以及发展全球健康计划 评估工具。该奖项还将支持获得R01资金所需的初步研究成果，以 将公平规划工具扩大到全球卫生研究的其他地理领域和领域。该工具具有 协助确保国际上正在进行的研究实践、成果和遗产 研究合作使研究合作伙伴都受益，并最终惠及他们所服务的全球社区。

ABSTRACT The Fogarty International Center is at the forefront of advancing National Institutes of Health (NIH) support for international research to promote health and reduce disease burden globally. A large part of this mission is linked to the successful creation and maintenance of international partnerships between institutions and research groups in low- and middle-income countries (LMICs) and high-income countries (HICs). Equity between LMIC and HIC research partners - defined as the prioritization of mutually beneficial inputs, processes, outputs, outcomes, and impact - is an ethical and practical imperative needed to achieve meaningful scientific aims and outputs within these partnerships that function in an inherently inequitable world. Despite the importance of establishing formal equitable practices and several recommendations and guidelines available to do so, tools for systematically acknowledging existing partnership inequities and methods to overcome them are not well-described. The goal of this proposal is to develop and pilot a pragmatic equity planning tool using experienced HIV- focused research partnerships between Uganda, an LMIC, and the United States (US), a HIC, as a case series given the dominance of the HIV epidemic on global health research paradigms over the past 40 years and the continued focus as a priority for many research partnerships in Uganda and the US. This will be accomplished through an explanatory quantitative to qualitative evaluation of these partnerships that generates a holistic understanding of best practices and barriers to equitable research practices (Aim 1). These results will inform the creation of an equity planning tool that consists of structured survey and focus group materials to systematically evaluate an international research partnership and create a summative report that highlights exemplar practices, identifies feasible areas for improvement, generates attainable program-level equity goals, and creates an action plan to achieve those goals (Aim 2). The equity planning tool will then be prospectively piloted and assessed for efficacy, feasibility, and acceptability within a research partnership (Aim 3). Collectively, this proposal seeks to elucidate a tool to recognize and, importantly, rectify equity-related issues and instigate change at a program level within international research partnerships. This K01 will provide Dr. Chelsea Modlin with the training she requires in advanced qualitative and ethnographic methods including reflexivity, empiric and applied methods in international research ethics, and developing global health program assessment tools. This award will also support preliminary research findings needed to pursue R01 funding to scale up the equity planning tool to other geographic areas and fields of global health research. This tool has the potential to assist with ensuring that the ongoing research practices, outputs, and legacies of international research collaborations benefit both research partners and ultimately, the global communities they serve.