Human Tumor Atlas Network: Data Coordinating Center Extension

项目摘要/摘要 我们建议继续管理数据协调中心(DCC) 人类肿瘤图集网络(Htan)，负责管理、策划和 传播通过该网络产生的数据和资源。我们已经提供，并且 将继续提供关键服务，以组织和支持研究中心 组成网络，并培育基于协作、透明和 分享。我们的主要科学目标是加速发现 肿瘤的发生、发展和演变，这将导致改进预防和治疗 为病人制定的策略。我们的目标是通过提供技术服务来实现这一目标 加速数据获取和向Htan研究人员传播的最佳做法 更广泛的科学界。Htan数据现在可通过Htan数据门户、 Synapse Platform、Minerva、CellXgene、cBioPortal、Google BigQuery、NCI癌症研究 数据服务(CDS)和NCI图像数据共享(IDC)。我们将继续发布 Htan数据提供给更广泛的科学界，并进一步开发可视化、注释和 分析工具，以满足Htan和多样化的癌症研究社区的需求- 包括数据科学家和统计学家到生物学家和临床医生-随着新类型数据的出现 已生成。

Project Summary/Abstract We propose to continue managing the operations of the data coordinating center (DCC) for the Human Tumor Atlas Network (HTAN) with responsibilities for managing, curating, and disseminating the data and resources generated through this network. We have provided, and will continue to provide, key services to organize and support the Research Centers that comprise the network, and foster a community based on collaboration, transparency, and sharing. Our primary scientific objective is to accelerate the discovery of mechanisms governing tumorigenesis, progression, and evolution, which will lead to improved prevention and treatment strategies for patients. We aim to achieve this by providing technology services coupled with best practices to expedite data acquisition and dissemination to HTAN researchers, as well as the broader scientific community. HTAN data is now available via the HTAN Data Portal, the Synapse platform, Minerva, CellXGene, cBioPortal, Google BigQuery, the NCI Cancer Research Data Service (CDS) and the NCI Image Data Commons (IDC). We will continue to release HTAN data to the wider scientific community and further develop visualization, annotation, and analysis tools in order to meet the needs of HTAN and the diverse cancer research community – including data scientists and statisticians to biologists and clinicians – as new types of data are generated.