Coordinating Center for Research Centers for Improving Management of Symptoms During and Following Cancer Treatment

项目摘要 推进Beau Biden Cancer MoonshotSM倡议，以加速癌症研究和蓝丝带计划 专家组的建议，以尽量减少癌症治疗的衰弱副作用，RTI国际将继续 作为研究中心（RC）的协调中心（CC），以改善管理， 癌症治疗中的症状（IMPACT）联盟。作为CC，RTI将提供领导，科学 专业知识和后勤支持，以联盟项目，寻求改善症状管理， 癌症治疗连续体（即，以治愈为目的的治疗，以非治愈/姑息为目的的治疗， 癌症存活率），并解决少数群体和医疗服务不足人群的独特挑战。 具体而言，我们将通过促进合作和提高研究效率、生产力和影响力， 为开展多中心研究提供必要的后勤、通信和操作支持 联盟;促进基于以下方面的循证症状管理建议的制定： 在研究和研究地点取得成果;加快采用综合监测系统， 通过与RC合作广泛传播发现，管理患者报告的症状。这 应用具有特定的优势，将提高该联盟的科学生产力。CC将 促进IMPACT联盟内部的合作，将不同的研究人员团结在共同的目标周围， 协调研究。RTI将通过开发和维护自定义网络来促进有效的沟通， 基于工具的通信和文档共享。RTI将利用数据标准和协调 以促进数据共享和聚合。

Project Summary To advance the Beau Biden Cancer MoonshotSM Initiative to accelerate cancer research and the Blue Ribbon Panel’s recommendation to minimize cancer treatment’s debilitating side effects, RTI International will continue to serve as the Coordinating Center (CC) for the Research Centers (RCs) for Improving Management of Symptoms Across Cancer Treatments (IMPACT) Consortium. As the CC, RTI will provide leadership, scientific expertise, and logistical support to the consortium projects that seek to improve symptom management across the cancer treatment continuum (i.e., treatment with curative intent, treatment with noncurative/palliative intent, cancer survivorship) and address the unique challenges of minority and medically underserved populations. Specifically, we will enhance research efficiency, productivity, and impact by facilitating collaboration and providing the logistical, communications, and operational support necessary to run a multicenter research Consortium; facilitate the development of evidence-based symptom management recommendations based on results across studies and research sites; and accelerate adoption of integrated systems for monitoring and managing patient-reported symptoms by collaborating with RCs to broadly disseminate findings. This application has specific strengths that will enhance the scientific productivity of the Consortium. The CC will foster collaboration within the IMPACT Consortium by uniting diverse researchers around shared goals and harmonized studies. RTI will promote effective communication by developing and maintaining custom web- based tools for communications and document sharing. RTI will leverage data standards and harmonization across the Consortium to catalyze data sharing and aggregation.