Molecular Biology of Muscle Development and Regeneration

描述（由申请人提供）： 这是一项建议，要求部分支持召开一次关于“肌肉发育和再生的分子生物学”的国际会议，该会议将于2003年5月30日至6月4日在阿尔伯塔班夫的班夫中心举行。会议的重点是分子信号和机制，诱导和调节肌肉发生，神经肌肉相互作用，和骨骼肌的人类疾病。10次全体会议，60名发言者（常设职等和初级职等）将处理：胚胎中的体细胞发生和肌发生，肌发生诱导和特化，肌肉中基因调节的蛋白质和信号网络，胚胎和成人中的肌发生干细胞，肌肉组织的形态发生和图案化，神经-肌肉相互作用，肌发生和肌肉再生中的细胞周期控制和细胞凋亡，肌肉可塑性和专业化，遗传学，机制和肌病疾病的治疗。三个晚上的海报会议将集中在：肌生成诱导和肌肉发育的调节，肌肉再生和疾病的分子生物学，以及肌肉基因调节，细胞迁移和神经支配的分子生物学。此外，由选定的发言者主持的圆桌会议将进一步讨论具体专题。本次会议是独一无二的肌肉生物学社区，因为它的使命，汇集了世界上的专家在基础科学的肌肉发育和分子生物学寻求推进诊断，预防和治疗肌肉疾病的人类。该会议每三年举行一次，二十年来，最初作为Keystone研讨会，自2000年以来独立举行。最近在加州的阿西洛马举行的会议吸引了来自地球仪的337名与会者。他们预计，自2000年5月在阿西洛马举行的会议以来，基因组学、细胞和分子生物学方面的重大进展将使即将在班夫举行的这次会议成为基础肌肉发育和疾病领域工作者相互学习的重要聚会，从而促进思想的交流和进一步的进步。

DESCRIPTION (provided by applicant): This is a proposal to request partial support to convene an international meeting on "Molecular Biology of Muscle Development and Regeneration" to be held at The Banff Centre in Banff, Alberta, from May 30 - June 4, 2003. The conference focuses on molecular signals and mechanisms that induce and regulate myogenesis, nerve-muscle interactions, and human diseases of skeletal muscle. Ten plenary, sessions presenting 60 speakers (at both established and junior levels) will address: Somitogenesis and myogenesis in the embryo, myogenic induction and specification, proteins and signaling networks for gene regulation in muscle, myogenic stem cells in embryos and adults, morphogenesis and patterning of muscle tissues, nerve-muscle interactions, cell cycle control and apoptosis in myogenesis and muscle regeneration, muscle plasticity and specialization, genetics, mechanisms and therapy of myopathic diseases. Three evening poster sessions will focus on: regulation of myogenic induction and muscle development, molecular biology of muscle regeneration and disease, and molecular biology of muscle gene regulation, cell migration and innervation. In addition, round-table sessions led by selected speakers will allow further discussion on specific topics. This conference is unique in the muscle biology community because of its mission to bring together the world's experts in fundamental science of muscle developmental and molecular biology seeking to advance diagnosis, prevention and therapy of muscle diseases in human. This conference has been happening every three years for two decades, initially as a Keystone Symposium and independently since 2000. The most recent conference held in Asilomar, California attracted 337 participants from around the globe. They expect the major advances in genomics, cellular and molecular biology that took place since the May 2000 conference in Asilomar will make this upcoming meeting in Banff an essential gathering for workers in both basic muscle development and disease to learn from each other and therefore stimulate a cross fertilization of ideas and further advances.