New Sterilization Method for Contact Lenses and Cases

描述（由申请人提供）：隐形眼镜（CL）是一种成功的视力控制形式，全球佩戴CL的人数已增至8500万-全国3200万。许多CL佩戴者没有意识到潜在的风险。CL配戴最严重的并发症是由微生物角膜炎（MK）引起的危及视力的角膜溃疡。据估计，美国每年发生30，000例MK病例。使用CL，尤其是长戴型镜片，是MK的一个显著风险因素。美国眼科学会指出，“据报告，CL使用者中CL消毒不充分、CL储存盒污染和CL溶液污染的发生率很高<in patients with MK>。“为了降低CL相关MK的风险，迫切需要改进护理产品和用户遵守推荐的透镜护理制度。只有25- 35%的CL配戴者遵循所有推荐的透镜护理说明。提出了一种用于CL和透镜盒的新灭菌方法，该方法应通过简化其透镜护理方案来提高患者依从性，并提供优于当前消毒剂的显著优势-在低两个数量级的浓度下，所提出的杀生物剂比过氧化氢对更广泛的生物体更有效。

DESCRIPTION (provided by applicant): Contact lenses (CLs) are a successful form of vision control, and the number of people wearing CLs has swelled to 85 million worldwide-32 million nationwide. Many CL wearers are unaware of the potential risks. The most serious complication of CL wear is sight threatening corneal ulceration caused by microbial keratitis (MK). An estimated 30,000 cases of MK occur annually in the US. The use of CLs, especially extended wear lenses, is a significant risk factor for MK. The American Academy of Ophthalmology states, "High prevalence of inadequate CL disinfection, CL storage-case contamination, and contaminated CL solutions among CL users have been reported <in patients with MK>.' To reduce the risk of CL-associated MK, improvements in tens care products and users compliance with recommend lens care regimes are desperately needed. Only 25-35 percent of CL wearers follow all of their recommended lens care instructions. A new sterilization method is proposed for CLs and lens cases that should improve patient compliance by simplifying their lens care regime and offer significant advantages over current disinfectants-at two orders of magnitude lower concentration the proposed biocide is more effective than hydrogen peroxide against a broader range of organisms.