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中文摘要
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核心A:行政核心摘要/摘要 MD安德森癌症中心卵巢癌SPORE的总体目标是将高质量的研究成果转化为 改善卵巢癌患者的临床结果。为了确保SPORE的成功, 行政核心将为与每个项目有关的所有活动提供有效的管理和行政, 核心,职业提升和发展计划的SPORE。行政核心将沟通 并在我们的SPORE调查人员之间传播信息,促进信息共享和合作 与其他SPORE和外部合作者。核心将提供一个平台, 将多学科整合为统一的多学科方法,以实现转化性卵巢癌的卓越治疗 research.行政核心将监测时间表,并确保基础科学和临床试验目标 为所有的SPORE项目。联合核心董事和MPI,Anil Sood博士和Robert Bast博士,沿着卵巢癌 孢子管理员Ersulan汉普顿女士和卵巢孢子科学作家Robert兰利博士将指导 行政核心的目标。核心的目标是:1)指导规划和评价, 确保整个战略研究和环境研究的科学质量和战略方向; 2)管理所有的财政和预算问题 所有项目、核心和发展研究以及职业发展计划; 3)监控数据 共享SPORE的合规性,以遵守所有一般政府和特定NCI法规, 要求; 4)协调质量保证活动,包括在 生物信息学和生物统计学核心和病理学核心; 5)作为SPORE的通信枢纽 向调查人员提供最新的操作信息; 6)与NCI项目官员沟通和协商 和其他员工,以确保所有必要的报告要求得到满足,包括PMCID政策合规性; 7)协调发展研究和职业发展计划的年度遴选过程 (c)确保妇女和女童的就业机会,并制定政策和程序,成功征聘妇女, 代表性不足的少数民族参加这些计划,并确保获奖者得到出色的指导; 8)确保SPORE融入机构的行政组织; 9)发起和协调内部 SPORE和机构间的互动和研讨会; 10)促进科学争议的解决;以及11) 组织并保持患者倡导者参与SPORE。
英文摘要
Core A: Administrative Core SUMMARY/ ABSTRACT The overall goal of the MD Anderson Cancer Center SPORE in Ovarian Cancer is to translate high-quality research into improved clinical outcomes for women with ovarian cancer. To ensure the success of the SPORE, the Administrative Core will provide effective management and administration of all activities relating to each project, core, career enhancement and developmental program in the SPORE. The Administrative Core will communicate and disseminate information between our SPORE investigators and facilitate information sharing and collaborations with other SPOREs and external collaborators. The Core will provide a platform for integrating diverse scientific disciplines into a unified multidisciplinary approach for achieving excellence in translational ovarian cancer research. The Administrative Core will monitor timelines and ensure both basic science and clinical trial aims are met for all SPORE projects. Co-Core Directors and MPIs, Drs. Anil Sood and Robert Bast, along with Ovarian SPORE Administrator, Ms. Ersulan Hampton and Ovarian SPORE Scientific Writer, Dr. Robert Langley, will direct the objectives of the Administrative Core. The objectives of the Core are to: 1) direct the planning and evaluation to ensure the overall scientific quality and strategic direction of the SPORE; 2) manage all fiscal and budgetary issues across all Projects, Cores and Developmental Research and Career Enhancement Programs; 3) monitor the data sharing compliance of the SPORE to adhere to all general governmental and specific NCI regulations and requirements; 4) coordinate quality assurance activities, including data quality controls with support from the Bioinformatics and Biostatistics Core and the Pathology Core; 5) serve as the communication hub for the SPORE to provide up-to-date operating information to investigators; 6) communicate and confer with the NCI Project Officer and other staff to make certain all necessary reporting requirements are met, including PMCID policy compliance; 7) coordinate the annual process for selection of Developmental Research and Career Enhancement Program recipients, and establish policies and procedures that result in the successful recruitment of women and underrepresented minorities to these programs and ensure awardees are supported with outstanding mentorship; 8) ensure the SPORE is integrated in administrative organization of the institution; 9) initiate and coordinate inter- SPORE and inter-institutional interactions and seminars; 10) facilitate resolution of scientific disputes; and 11) organize and maintain patient advocate involvement in the SPORE.
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Targeting EGFL6 in Ovarian Cancer
Harnessing the power of exosomes for non-coding RNA delivery
Harnessing the power of exosomes for non-coding RNA delivery
Developmental Research Program
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