Outreach Core

外展项目摘要。 ST分析科学计划旨在采用系统生物学方法来解决 如何有效地施用靶向抑制剂-免疫疗法序贯组合以治疗 治疗实体瘤，重点是黑色素瘤。ST Analytics采用最先进的 实验和计算程序相互密切反馈， 溶液ST-Analytics外联计划是一个高度互补的计划， 与U 54的核心科学主题相一致的外联目标。外展计划利用了 ISB的“系统教育经验”教师教育计划，促进系统的方法， 通过开发提供积极STEM的教育模块来解决科学问题 为全球50个州的数百万学生提供学习体验。重点是 放置在提供系统免疫肿瘤学实习和经验，以学生群体传统上 在STEM领域的代表性不足。基本方法是将这些实习生与ST分析整合 研究人员将系统免疫肿瘤学概念纳入两个现有或正在开发的教育 模块，题为系统医学模块3 -个性化疾病治疗，并通过 系统思维和计算建模。虽然这些模块旨在满足下一代 科学标准（NGSS），负责实施这些标准的专业教育工作者经常 没有适当的背景或支持材料的工作。因此，我们的推广计划也是 旨在提供这种背景和支持。例如，我们提供以研究为基础、以现实为驱动的 每年为1 000多名教师和80名地区行政人员提供专业发展， 华盛顿三分之二的学生。因此，ST-Analytics外展计划的潜在影响很大， 并通过利用广泛的现有资源和关系来实现，这些资源和关系延伸到整个州， 华盛顿州和美国西海岸的上下。一个吸引所有参与者创造性参与的计划 在我们提出的U 54计划中，各级都有描述。

Outreach. Project Summary. The ST-Analytics scientific program is designed to take a systems biology approach towards addressing the question of how to effectively administer targeted-inhibitor – immunotherapy sequential combinations for the treatment of solid tumors, with an emphasis on melanoma. ST Analytics incorporates state-of-the-art experimental and computational programs advancing in close feedback with each other towards a robust solution. The ST-Analytics Outreach Program is designed as a highly complementary program, with STEM outreach goals that are aligned with the core scientific theme of the U54. The Outreach program takes advantage of ISB’s ‘Systems Education Experiences’ teacher Educational Programs that promote systems approaches to scientific problem solving through the development of educational modules that have provided positive STEM learning experiences for millions of students worldwide, and in each of the 50 states. A strong emphasis is placed on providing systems immuno-oncology internships and experiences to student populations traditionally under-represented in the STEM fields. The basic approach is to integrate these interns with ST-Analytics researchers to incorporate systems immuno-oncology concepts into two existing or in-development educational modules, entitled Systems Medicine Module 3 - Personalizing Disease Treatments, and Gaining Insight through Systems Thinking and Computational Modeling. While those modules are designed to meet Next Generation Science Standards (NGSS), the professional educators who are tasked with implementing those standards often do not have the proper background or supporting materials for the job. Thus, our outreach programs are also designed to provide that background and support. For example, we provide research-based, reality-driven professional development for more than 1,000 teachers and 80 district administrators annually, impacting over two-thirds of students in Washington. Thus, the potential impact of an ST-Analytics outreach program is large, and is achieved by leveraging extensive existing resources and relationships that extend throughout the state of WA and up and down the U.S. west coast. A program that solicits creative engagement from all participants within our proposed U54 program at all levels is described.